Paper Type	::	Research Paper
Title	::	The Challenges to Advanced Diabetic Care Practice in the UAE Community Settings
Country	::	United Arab Emirates
Authors	::	Rana Mohammed Ghazal || Ola Al Ahdab
Page No.	::	01-06

over the past few decades remarkable growth of pharmacy practice and the managed care system have been noticed. The concept of The Pharmaceutical Care Practice evolved to help maximize the contributions of pharmacists in improving Diabetic patients' outcomes and decrease health care costs. Despite of the fact that pharmaceutical literatures will continue to provide evidence references to identify the unique contribution that pharmacists can make to Diabetic Management and health improvement, many pharmacists are not routinely engaging in Pharmaceutical Care activities because of the variety of obstacles. Hence, pharmacists' perception about the new emerging philosophy of the Advance Diabetic Care Practice and its challenges are at vital concern........

 

Keywords: Advance Diabetic Care, challenges, community settings, growth of pharmacy practice

[1] Manasse Jr, H. R., & Thompson, K. K. (Eds.). (2005). Medication safety: a guide for health care facilities. ASHP.
[2] Strand, L. M., Cipolle, R. J., Morley, P. C., & Perrier, D. G. (1991). Levels of pharmaceutical care: a needs-based approach. Am J Hosp Pharm, 48(3), 547-550.
[3] Johnson, J. A., & Bootman, J. L. (1995). Drug-related morbidity and mortality: a cost-of-illness model. Archives of Internal Medicine, 155(18), 1949.
[4] Armor, Becky L., and Mark L. Britton. "Diabetes mellitus non-glucose monitoring: point-of-care testing." The Annals of pharmacotherapy 38.6 (2004): 1039-1047.
[5] Benrimoj, S. I., & Frommer, M. S. (2004). Community pharmacy in Australia.Australian Health Review, 28(2), 238-246.

Paper Type	::	Research Paper
Title	::	Moringa oleifera leaf extract inhibits diabetogenic effect of alloxan in rats
Country	::	Nigeria
Authors	::	Olubunmi Adebambo Onyagbodor || Jonah Sydney Aprioku
Page No.	::	07-12

This study investigated the protective and ameliorative potential of ethanol extract of Moringaoleifera leaf (50-200 mg/kg) on alloxan-induced diabetes in Wistar rats. Alloxan-induced diabetic rats were orally pretreated with extract (50, 100 or 200 mg/kg) or post-treated with extract (50, 100 or 200 mg/kg/day), glibenclamide (2.5 mg/kg/day) or metformin (200 mg/kg/day) for two weeks. Other animals received only extract, alloxan (diabetic control) or vehicle (control). Blood glucose concentrations were measured at the beginning and twice weekly. Glucose levels in extract pretreated rats were lower (p<0.05)than alloxan-induced levels, but when compared with control, were higher except that glucose level was normalized from the 11th day in 200 mg/kg extract pretreated rats............

 

Keywords: Alloxan, antioxidants, diabetes, Moringa

[1] H. King, R.E. Aubert, and W.H. Herma, Global burden of diabetes 1995-2025: Prevalence, numerical estimates and projection. Diabetes Care, 21, 1998, 1414-1431.
[2] International Insulin Foundation. Fact Sheet on diabetes in sub-Saharan Africa. International Insulin Foundation, London, 2005.
[3] C.J. Bailey, and L. Dey. Traditional plant medicine, as treatment for diabetes. Diabetes Care, 12, 1989, S53-S64.
[4] World Health Organization (WHO). Study Group Report on Prevention ofDiabetes mellitus. WHO, Geneva, 1994, 1-92.
[5] F. Anwar, S. Latif, M.Ashraf, and A.H. Gilani. Moringaoleifera: a food plant with multiple medicinal uses. Phytotherapy Research, 21, 2007, 17-25.

Paper Type	::	Research Paper
Title	::	The Level Of Legumes Supplementation In The Basal Diet Of Rice Straw On Intake And Digestibility Of Ongole Crossbred Cows
Country	::	Timor-Leste
Authors	::	Nolasco Da Costa || Cristela Da Costa
Page No.	::	13-19

The purpose of this study was to know the effect of different level of supplementating legumes in basal diet of rice straw (RS) on feed intake and digestibility of Ongole crossbred (PO) cows. As of 20 Ongole filial bull s (initial weight of 308.25 ± 38.36 kg, aged I 3 – I 4) were grouped into four treatments such as: R0 = RS (ad-libitum), R1 = RS + (gliricidia + leucaena 0.25% of LW (DM basis), R2= RS + (gliricidia and leucaena 0.5% of LW), R3 = RS + (gliricidia and leucaena 1.0 % of LW). So, in each treatment consisted of five animals as replication. Parameter measured were: intake of dry matter (DM), organic matter (OM) and crude protein (CP) and the in vivo digestbility of DM, OM and CP. Data analyzed by using completely randomized design. Results showed that supplementing legumes in basal diet of RS was influence (P < 0.01) DM, OM and CP intake.........

 

Keywords: Legume, rice straw, feed intake, digestibility, cows

[1] Balakely, J and D. H. Bade. 1985. The Science of Animal husbandry 4th edition.
[2] Bonga, S.M.D. 2003. Addition of Ongole Peranakan Beef Body Weight Rice Feeding Basal Straw Rice and Smooth Bit with Additive Microbial Culture. Essay. Faculty of Animal Husbandry Universitas Gadjah Mada. Yogyakarta.
[3] Church D. C, 1980. Digestive Physiology and Nutrient Of Ruminants. Volume 1,
[4] De Jong, R, and J. Van Burhem, 1993. Utilization of Crop Residues and Supplementary Feeds in Tropical Developing Countries. Final report of Research, Commission of the European Comunities,Waginengen, The Netherlands.\Digestive Physiology.
[5] Djajanegara, A. 1983. Review of Evaluation of Supplements on Rice Straw. Pros. Seminar on Utilization of Food Waste and Agricultural Waste for Livestock Food. LIPI. Edition. Longhman Scientific and Technical. New York. Grouth Published by AUIDP and AAUCS. Canberra.

Paper Type	::	Research Paper
Title	::	Subchronic Toxicity Study of Hydroethanolic Extract of Delphinium Denudatum Root And Amaranthus Spinosus Leaves on Experimental Rats
Country	::	India
Authors	::	Mohd. Abid || Tahira Sultan || Naman Gupta || Alankar Shrivastav || Najam Ali Khan
Page No.	::	20-25

Object: The objective of this study is to evaluate subchronic toxicity study of hydroethanolic extract of hydroalcohlic extract of Delphinium denudetum root, Amaranthus spinosus leaves. Products that obtained from plants have been used for medicinal purposes. Approximately about 80% of the world population today, relies on natural drugs to meet their health needs [1]. The problem with the natural preparations as drugs is that most of the plants are been used indiscriminately without adequate information on associated safety/ toxicity risks. It was thought that natural drugs considered being safe but it is proved to be toxic.Therefore, there is a need to be
maintaining the proper knowledge, safety/ toxicity profile and scientific documentation guidance of these natural products.........

 

Keywords: Toxicity, hematological, Biochemical, Delphinium denudetum, Amaranthus spinosus.

[1]. K Polasa, and K Nirmala. Ginger: Its Role in Xenobiotic Metabolism. ICMR Bull, 2003; 33: Suppl 6: 57- 63.

[2]. J.F Deng. Clinical Toxicity of Herbal Medicine in Taiwan. Proceedings of the 7th International Conference on Health Problems Related to the Chinese in North America, July 1-3, 1994, New York, USA.

[3]. N Qudsia, & M.A. Jafri. Unani drug, Jadwar (Delphinium denudatum Wall.) - A review. Indian Journal of Traditional Knowledge, 2006; 5(4): 463-467.

[4]. S Zafar, M.A. Aftab, & TA. Siddiqui. Jadwar (Delphinium denudatum Wall.) Roots – A Boon in Unani Medicine. Hamdard Med, 6(2), 2003, 9-14.

Paper Type	::	Research Paper
Title	::	Explorative Study Through Survey, Monitoring And Diagnosis Diseaseofbali Cattle In Mehara District Of Lautem
Country	::	Timor-Leste
Authors	::	Nolasco Da Costa || Andre Do Carmo
Page No.	::	26-33

The research aimed to obtain information from farmers about animal health business. Examination of animal health physiology status through pulsus measurement, breath frequency, rectal temperature, habitus, and nutritional status. The method used is Explorative Study approach. Data were obtained through interviews with 50 farmers, checking the health status of livestock, reviewing livestock raising systems in the field and taking blood for disease diagnosis. Interviews gathered information on livestock raising in terms of feeding aspects (types of feed given and feeding methods), aspects of marriage (marriage method and identification of livestock) and reviewed from health aspects (vaccination program, worm medication and drug administration ) to livestock if cattle are sick.........

 

Keywords: Eksploratif, Monitoring Diagnosis DiseaseBali Cow.

[1] Abidin Z. 2002.Tips to Overcome Practical Problems Cow FatteningCut. Jakarta (ID): AgromediaPustaka.
[2] Agustini NLP. 2011. Surveillans of Jembrana disease in Bali, Lampung and Nangroe provinces.
[3] Akoso BT. 1996. Cattle Health. Yogyakarta (ID): Kanisius.
[4] Arthur GH, Noakes DE, Pearson H. 1989. Veterinary Reproduction andObstetrics (Theriogenology). London (UK): BailliereTindall.
[5] Bandini Y, (1997). Bali Cow.Publisher PT.The Swadaya spreader.Dharma, D.N, A.A.G., Son, (1997).Disease InvestigationsAnimal.C.V. Bali Media Adhikarsa.Denpasar.

Paper Type	::	Research Paper
Title	::	Substitution Of Concencrate With Silage Of Cassava Leaf (Manihot Esculenta,Crantz) And Gliricidia (Gliricidia Sepium, Jacq.) Mixtures On Feed Consumption And Average Daily Gain Of Goat
Country	::	Timor-Leste
Authors	::	Nolasco Da Costa
Page No.	::	34-38

The purpose of this research was to study substitution of concencrate with silage of cassava leaf (Manihot esculenta, Crantz) and gliricidia (Gliricidia sepium,Jacq.) mixtures on feed consumption and average daily gain of Goat. Materials used in this experiment were 20 Goat at early average body weight 23.85 kg ± 4.75 and coeficient of variance 19.94%. They were arranged in Randomaized Block Design with 5 treatments that were replicated 4 blok. Feed used were Corn Leaf (CL), Concentrate (C) and cassava leaf and gliricidia mixture Silage (S), with ratio corn leaf and concentrate were 60%:40% dry matter basis. Five dietary treatments applied were: RO: corn leaf 60% and concentrate 40% (Concentrate 100% and Silage 0%), K2: corn leaf 60% and concentrate 40% (Concentrate 75% and Silage 25%), K3: corn leaf 60% and concentrate.........

 

Keywords: Cassava Leaf, Gliricidia, Silage, Concencrate, Goat.

[1] Agriculture department. 1997. Cassava Leaves and Utilization as Animal Feed. Section of Agricultural Technology Assessment Project. Yogyakarta.
[2] Doyle, 1986. Nutritional and Feeding Strategies for Goat in Asia. Proc. Of The Workshop on Goat Production In Asia. IDRC. Manila.
[3] Evans. 1981. A Dynamic Model of Crude Protein Digestion and Utilization in Ruminants. J. Anim. Sci. 55 (1): 419.

[4] Forbes, J. M., 1986. The Voluntary Feed Intake of Farm Animals. Butterwoth & Co., Ltd. London.
[5] Greehalgh, J.F.D., O.R., Orskov and S., Froser, 1976. Pelleted Herbage for Intensive Lamb Production. Animal Production. (22): 148-149.

Paper Type	::	Research Paper
Title	::	Antibacterial Activity of Honey Samples on Methicillin Resistant Staphylococcus Aureus (MRSA) Isolated From Human Conjunctiva
Country	::	India
Authors	::	Jayanthi N || Asokan S
Page No.	::	39-45

Honey exhibits antimicrobial activities against different types of bacteria in world wide. This study
aims to analysis the antimicrobial effects of three types of honey (named as S1, S2 &S3) obtained from different places of Theni district, South India against methicillin resistant Staphylococcus aureus isolated from human conjunctiva. Three honey samples are subjected to antimicrobial activity with different dilutions (0%), (25%), (50%), (75%) and (100%) against MRSA method. In 100% dilution of S1 sample showed maximum zone of inhibition (14±0.0mm) was observed. Three honey samples were extracted with various solvents such as ethanol, methanol and ethyl acetate and antimicrobial activities of honey extractions were analyzed. Methanol extract of S1 sample showed maximum zone of inhibition (14±0.0mm) was observed. The MIC of methanol extract of S1 sample showed better bacteriostatic activity at 3.12%. From this study we found S1 sample have
better antibacterial activity than S2 and S3 sample against MRSA isolated from humanconjunctiva.

 

Keywords: Conjunctiva, MRSA, honey, disc diffusion method, MIC

[1] Snyder R, Glasser D. Antibiotic therapy for ocular infection. West J Med. 1994;161(6):579–584.
[2] Hovding G. Acute bacterial conjunctivitis. Acta Ophthalmol. 2008;86(1):5–17.
[3] Rose P. Management strategies for acute infective conjunctivitis in primary care: a systematic
review. Expert Opin Pharmacother. 2007;8(12):1903–1921.
[4] Stratton CW. Dead bugs don't mutate: susceptibility issues in the emergence of bacterial
resistance. Emerg Infect Dis. 2003;9(1):10–16.
[5] Hryniewicz W. Epidemiology of MRSA. Infection 1999; 27 Suppl. 2: S13−S15. |

Paper Type	::	Research Paper
Title	::	A Study on the applications of Silver nanoparticles synthesized usingaqueous extract and purified secondary metabolites of seaweed Hypneacervicornis
Country	::	India
Authors	::	Leela.K || Anchana Devi.C
Page No.	::	46-61

Seaweeds are commonly referred to as macroalgae and are plant like organisms that live attached to rock or any other hard substrata. They are one among the commercially important sources which possess the ability to synthesize numerous secondary metabolites that have wide applications in the field of medicine as anti-inflammatory or anticancer agents. They are also widely utilized in the production of polysaccharides such as carrageenan, fucoidan etc., and have both therapeutic as well as industrial applications. The Present study was carried out on the synthesis, characterization and applications of silver nanoparticle using the aqueous extract and the individual purified compounds of Seaweed Hypneacervicornis.........

 

Keywords: Hypneacervicornis, Silver nanoparticle, Secondary compounds, UV-Visible pectroscopy, Fourier transform infrared spectroscopy, Scanning electron microscope, Applications.

[1]. Johnson Marimuthu, PetchiammalEssakimuthu, JanakiramanNarayanan,BabuAnantham,Renisheya Joy
Jeba malar Tharmaraj,SivaramanArumugam. Phytochemical characterization of brown seaweed
Sargassumwightii.Asian Pacific Journal of Tropical diseases. 2012. pp: 109-113.
[2]. Kiriyama S, Okazaki Y, Yoshida A.Hypocholesterolemic effect of polysaccharides and polysaccharide foodstuffs in cholesterol fed rats.J. Nutr.1968. pp:382–388.
[3]. Littler DS, Littler MM, Bucher KE, Norris JN.(Ed.3).Marine Plants of the Caribbean, a Field Guide from Florida to Brazil. Washington, DC: Smithsonian Institution Press.1989.
[4]. Rai M., Yadav A. and Gade A. Biotech. Adv., vol.27.2009.pp: 76-83.
[5]. Ahamed M, Alsalhi.M. S, Siddiqui.M. K. J. Clinicachimicaacta. 2010. pp: 1841-1848.

Paper Type	::	Research Paper
Title	::	Activity of Picroliv Isolated from Picrorhiza kurrooa against Thioacetamide and Entamoeba histolytica Induced Liver Damage
Country	::	India
Authors	::	Madhulika Singh || Sheela Ghoshal
Page No.	::	62-68

Picroliv, an iridoid glycoside mixture, isolated from root and rhizome of Picrorhiza kurrooa known to possess significant hepatoprotective activity. Present study demonstrated the hepatoprotective potential of picroliv against thioacetamide and Entamoeba histolytica induced hepatic damage in rats, mastomys, and gerbils. Significant increase in the serum levels of hapatospecific markers was found due to administration of hepatotoxic agent, thioacetamide (200mg/kg b. wt.), indicating wide spread liver damage in the test models which was further elevated after E. histolytica infection. Pinpoint amoebic liver abscesses were found to develop only in gerbils. Administration of picroliv (12 mg/kg b. wt.) resulted in significant recovery of altered serum levels of albumin, protein, triglycerides and cholesterol in all animal models challenged with thioacetamide and E. histolytica..........

 

Keywords: Entamoeba histolytica, Hepatic amoebiasis, Hepatoprotective, Picroliv, Thioacetamide

[1] A.B. Vaidya, D.S. Antarkar, J.C. Doshi, A.D. Bhatt, V.V. Ramesh, P.V. Vora, D.D. Perissond, A.J. Baxi, P.M. Kale. Picrorhiza kurroa (Kutaki) Royle ex Benth as a hepatoprotective agent--experimental & clinical studies. Journal of Post Graduate Medicine, 42 (4), 1996, 105-108.
[2] P.C. Verma, V. Basu, V. Gupta, G. Saxena, L.U. Rahman. Pharmacology and chemistry of a potent hepatoprotective compound Picroliv isolated from the roots and rhizomes of Picrorhiza kurroa royle ex benth. (kutki). Curr Pharm Biotechnol., 10(6), 2009, 641-649.
[3] A. Krishnamurthy, The Wealth of India Vol. VIII p 49 (Publication and Information Directorate, Council of Scientific and Industrial Research, New Delhi, 1969).
[4] P.K.S. Visen, B. Shukla, G.K. Patnaik, R. Chandra, V. Singh, N.K. Kapoor, B.N. Dhawan, Hepataprotective activity of picroliv isolated from Picrorhiza kurrooa against thioacetamide toxicity on rat hepatocytes, Phytotherapy Research, 5, 1991, 224-227.
[5] R. Rastogi, A.K. Srivastava, A. K. Rastogi, Biochemical changes in liver and serum of aflatoxin B1 treated male Wistar rats: preventive effect of picroliv, Pharmacological Toxicology, 88, 2001, 53-58.

Paper Type	::	Research Paper
Title	::	Therapeutic Potential of Tropical Underutilized Legume; Mucuna Pruriens
Country	::	India
Authors	::	Rajiv Bharadwaj P || Dr. K S Chandrashekharaiah
Page No.	::	69-77

Therapeutic applications have become an important study to manage various systemic disorders faced by mankind due to genetic, environmental and lifestyle factors. Medicine systems have been contributing in greater aspect to effectively manage and control the disease at its minimal. However, there is always a need for profound research in finding better and more efficient way for disease management. Plants have been a great source of medicinal value used in various traditional and modern medicine systems. Mucuna pruriens, a tropical legume of Asia and Africa has been well characterized for its medicinal value. Bioactivity studies have shown a plethora of "anti" activities beneficial for therapeutic applications in Mucuna pruriens, making it an interesting plant for biochemical studies...........

 

Keywords: Bioactivity, legume, therapeutics, Genus Mucuna

[1] Adive B. I. Udedibie and Celia R. Carlini, Brazilian Mucuna pruriens Seeds (Velvet Bean) Lack Hemagglutinating Activity, J. Agric. Food Chem. 1998, 46, 1450-1452.
[2] Agbafor K. N., Nwachukwu .N, Phytochemical Analysis and Antioxidant Property of Leaf Extracts of Vitex doniana and Mucuna pruriens, Biochemistry Research International Volume 2011, doi:10.1155/2011/459839.
[3] Angiosperm Phylogeny Group, "An update of the Angiosperm Phylogeny Group classification for the orders and families of flowering plants: APG III". Botanical Journal of the Linnean Society 2009; 161 (2): 105–121. doi:10.1111/j.1095-8339.2009.00996.x.
[4] Anusha Bhaskar, V.G. Vidhya, M. Ramya, Hypoglycemic effect of seed extract on normal and streptozotocin-diabetic rats, Fitoterapia, Volume 79, Issue 7, 2008, Pages 539-543, ISSN 0367-326X, http://dx.doi.org/10.1016/j.fitote.2008.05.008.
[5] Article 18.5, Section 2, Chapter III, International Code of Nomenclature for algae, fungi and plants, International Association for Plant Taxonomy.

Paper Type	::	Research Paper
Title	::	Importance Of Self-Monitoring Of Blood Glucose In Gestational Diabetes: Pharmacists' Role In Improving Patient's Compliance - Pilot Study
Country	::	Bulgaria
Authors	::	Radiana Staynova || Stanislav Gueorguiev || Elina Petkova-Gueorguieva || Vasil Madzharov || Stanislava Ivanova || Kalin Ivanov
Page No.	::	78-82

Aim: The aim of the present study is to: (1) analyze the role of self-monitoring of blood glucose as a major component in assessing the overall control of gestational diabetes mellitus (GDM); (2) assess the role of pharmacist as a provider of pharmaceutical care for women with GDM. Materials and methods: A study was conducted among 30 women diagnosed with GDM in the period February 2017 - July 2017. For the purposes of the study an original questionnaire was used, which was filled in by the respondents during their visit to community pharmacies on the territory of Plovdiv, Bulgaria. All pregnant women participated voluntarily and anonymously. Data was statistically processed using MS Office Excel for Windows 10 and SPSS software v.17............

 

Keywords: Gestational diabetes mellitus, pharmaceutical care, self-monitoring of blood glucose

[1] Hod M, Kapur A, Sacks DA et al. The International Federation of Gynecology and Obstetrics (FIGO) initiative on gestational diabetes mellitus: a pragmatic guide for diagnosis, management and care. Int J Gynecol Obstet. 2015; 131(Suppl. 3): S173–211.
[2] Ferrara A, Increasing prevalence of Gestational Diabetes Mellitus: a public health perspective. Diabetes Care 2007; 30 (Suppl 2):141
[3] Benjamin E.M. Self-monitoring of blood glucose: The basics. Clin Diabetes. 2002; 20 (1): 45-47.
[4] Mensing C, Boucher J, Cypress M. et al. National standards for diabetes self-management education. Diabetes Care. 2006; 29 (Suppl 1): 78–85.
[5] Karter AJ, Ackerson LM, Darbinian JA, D'Agostino RB Jr, Ferrara A, Liu J, Selby JV: Self-monitoring of blood glucose levels and glycemic control: the Northern California kaiser permanente diabetes registry. Am J Med 2001, 111(1):1–9.