National Conference on Emerging Trends & Future Challenges in Chemical Sciences

Volume - 2


Paper Type

::

Research Paper

Title

::

Novel Green Synthesis of Zinc Oxide Nanoparticles & Study of Its Invitro Antimicrobial Activity

Country

::

India

Authors

::

N.Sachadanandam || D.Shakila || Kannappan Geetha || A.Dinesh Karthik

Page No.

::

01-06

Paper Index
::
XXXX

Green synthesis techniques make use of moderately pollutant free chemicals to synthesis nanometerials and embrace the use of benign solvents such as water, natural extracts. Green chemistry seeks to reduce pollution at source. Though physical and chemical methods are trendier for nanoparticles synthesis, the biogenic fabrication is a better choice due to eco-friendliness Nanoparticles due to their smaller size and large surface to volume ratio exhibit remarkable novel properties and methodical applications in the field of biotechnology, sensors, medical, catalysis, optical devices, DNA labeling, drug delivery and they are rewardingly treated as a bridge between bulk material and atomic and molecular structures. To Synthesize the Zn(OH)2 precursors from various aromatic acids like 3,5 Di Nitro Benzoic Acid, 3,5 Di Nitro Salicylic Acid..........

 

Keywords: ZnO, UV –Visible, XRD, FT-IR and Antimicrobial activity.

[1]. Tundo P. and Anastas P._. Eds, Green Chemistry Challenging Perspectives. Oxford University Press, Oxford, UK, (2000)
[2]. Reed S.M. and Hutchison J.E., Green Chemistry in the organic teaching laboratory: an environmentally benign synthesis of adipic acid, J Chem Educ 77, 1627 (2000)
[3]. Anastas P.T. and Warner J.C., Green Chemistry: Theory and Practice, Oxford University Press, New York, (1998).
[4]. Clark J., Macquarrie D., Handbook of Green Chemistry and Technology, Blackwell Publishing, Abingdon, Oxfordshire, (2002)
[5]. Fan Z. and Lu J.G., Journal of Nanoscience and Nanotechnology, 5 (10), 1561 (2005)

 

Paper Type

::

Research Paper

Title

::

Synthesis and Antioxidant ability of Nanofiber mat prepared using Polyvinyl alcohol and Montmorillonite clay

Country

::

India

Authors

::

K. Sangeetha || Faleh A.Alsharani || K. Vijayalakshmi || Sukumaran Anil || P.N. Sudha

Page No.

::

07-12

Paper Index
::
XXXX

Scaffold of Polyvinyl alcohol/Montmorillonite clay have been developed using electrospinning. SEM images of electrospun nanofiber mat showed that they had similar and smooth morphology without beads, and spindle shape. The addition of clay will results in decreasing the average fiber diameter and thereby increasing the surface area. The benefit of high surface area is obvious in drug delivery systems for poorly water-soluble drugs. Their FTIR spectra indicate that the PVA and MMT clay interacted intermolecularly via hydrogen bonds in the nanofiber mats. Their XRD patterns confirmed that they were amorphous, because of amorphization during electrospinning. The XRD analyses also strengthened the FTIR studies; namely, PVA and MMT formed intermolecular interactions in the electrospun nanofiber mats. From the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, the nanofiber mats exhibited very high antioxidant activities despite having been exposed to high voltage during electrospinning. Therefore, they are potential antioxidant products for food and pharmaceutics.

 

Keywords: Antioxidant, DPPH, Montmorillonite clay, Polyvinyl alcohol, Scaffold.

[1]. M.-X. Wang, Z.-H. Huang, F. Kang, and K. Liang, Porous carbon nanofibers with narrow pore size distribution from electrospun phenolic resins, Materials Letters, 65, 2011, 1875-1877.
[2]. M. Sadri, A. Maleki, F. Agend, and H. Hosseini, Fast and Efficient Electrospinning of Chitosan-Poly(ethylene oxide) nanofibers as potential wound dressing agents for tissue engineering, Journal of Applied Polymer Science, 126(6), 20112, 2077-2084.
[3]. X.J. Han, Coaxial Electrospinning of PC (Shell)/PU (Core) composite nanofibers for textile application, Polymer composites, 27, 2006, 381-387.
[4]. C.-I. Su, Pan-based carbon nanofiber absorbents prepared using Electrospinning, Fibers and Polymers, 13(4), 2012
[5]. X.-H.Qin, and S.-Y. Wang, Filtration properties of Electrospinning nanofibers, Journal of Applied Polymer Science, 102(2), 2006, 1285-1290.

 

Paper Type

::

Research Paper

Title

::

Novel Indole Derivatives with Improved Antimicrobial Activity

Country

::

India

Authors

::

P.Saravanan || M. Sathiya || S. Guhanathan

Page No.

::

13-20

Paper Index
::
XXXX

Heterocyclic compounds play a significant responsibility in the metabolism of living cell. Many of the heterocyclic compounds have pharmacological action and quantifiable uses. The chemistry of heterocyclic compounds had been an interesting field of study of long time. Chiefly, nitrogen containing heterocyclic compounds have customary special consideration in pharmaceutical chemistry due to their miscellaneous medicinal prospectives. Two set of compounds A and B have been synthesized in excellent yield through Fischer's indolosation method via acetic acid as a solvent. The synthesized compounds were characterized and established by various instrumental techniques viz, FTIR, 1H NMR, 13C NMR and Mass spectroscopy. The synthesized compounds were subjected to antimicrobial action. The outcome showed that the synthesized compounds exhibit brilliant antifungal activity than antibacterial activity.

 

Keywords: 2-pyrrolidinone, phenylhydrazine, acetic acid, ciprofloxacin, amphotericin-B.

[1]. Sundberg, R.J. Indoles; Acedemic press: New York, 1996
[2]. Robert, M., F; wink, M.Alkaloids: Biochemistry,Ecology,and Medicinal Applications; plenum: London,1998.
[3]. Von Nussbanm, F. Angew. Chem.., Int Ed. 2003, 42, 3068-3071
[4]. Pindur,. U.; Lemster, T Curr. Meel. Chem. 2001, 8, 1681-1698
[5]. Hesse, M.Alkaloids . Naturel and curse or Blessing ? ; wiley-VCH : Weinheim, 20002

 

Paper Type

::

Research Paper

Title

::

Synthesis And Antimicorbial Evaluation Of Indole Derivatives

Country

::

India

Authors

::

M. Sathiya || S. Guhanathan

Page No.

::

21-26

Paper Index
::
XXXX

Heterocyclic compounds constitute the core structure of a number of biologically interested compounds against microorganisms. The synthesis of substituted and condensed indole has been attracted many researchers due to their importance in biological activity. So far, five compounds has been synthesized by enhanced approach of Fischer's synthesis namely 1,2,3,4-tetra hydrocyclopenta(b)indole, 3,8-dihydro-2H-furo(2,3-b)indole, 5,6-dihydro-11H-benzo(a)carbazole, 6,11-dihydro diindolo(3,2b)carbazole and 12,12-dimethyl-6-hydro-indolo (3,2-b)carbazole. The formation of various compounds were confirmed by spectral techniques viz, FTIR, 1H NMR, 13C NMR, MASS Spectroscopy. A comparative study among the compounds of present investigation on antimicrobial evaluation reveals that all the compounds exhibit excellent antifungal activity than antibacterial activity.

 

Keywords: Alpha-tetralone, sulphuric acid, phenylhydrazine, ciprofloxacin, amphotericin-B.

[1]. Miller, B. Advanced Organic Chemistry: Reactions and Mechanisms. Pearson Education, Inc: Upper Saddle River, NJ, 2004; pp 372-373.

[2]. Fischer.E., "Molecular properties and transformations of glycogen phosphorylase in animal tissues." Adv Enzymol Relat Areas Mol Biol 14 (1962): 263-290.

[3]. Svoboda G.H, (1961). Alkaloids of Vinca rosea (Catharanthus roseus). IX. Extraction and characterization of leurosidine and leurocristine. Lloydia, 24, 173-178.

[4]. Dalton. L.K, Demerac, S., Elmes, B. C., Loder, J. W., Swan, J. M., & Teitei, T. (1967). Synthesis of the tumour-inhibitory alkaloids, ellipticine, 9-methoxyellipticine, and related pyrido [4, 3-b] carbazoles. Australian Journal of Chemistry, 20(12), 2715-2727.

[5]. Ding. L & Laurent, J. M. (1990). Simultaneous convective and diffusive mass transfers in a hemodialyser. Journal of biomechanical engineering, 112(2), 212-219.

 

Paper Type

::

Research Paper

Title

::

Preparation of Synthesis of 1-(Prop-2-Ynyloxy) Benzene Under A New Multi-Site Phase-Transfer Catalyst Combined With Ultrasonication –A Kinetic Study

Country

::

India

Authors

::

Nagendiran Kaviya || Dhanavel Prakash || Ansari Firose || Varathan Selvaraj || Venugopal Rajendran

Page No.

::

27-39

Paper Index
::
XXXX

In the present work, kinetics of synthesis of synthesis of 1-(prop-2-ynyloxy) benzene was successfully carried out by O-propargylation of phenol with propargyl bromide using aqueous potassium hydroxide and catalyzed by a new multi - site phase - transfer catalyst viz., 1,3,5,7-tetrabenzylhexamethylenetetraminium tetrachloride, MPTC under ultrasonic ( 40kHZ, 300W) assisted organic solvent condition. The pseudo first-order kinetic equation was applied to describe the overall reaction. Under ultrasound irradiation (40 kHz, 300 W) in a batch reactor, it shows that the over all reaction rates can be greatly enhanced to seven times faster with ultrasound irradiation than without using ultrasound. The present study provides a method to synthesize ethers by ultrasound assisted liquid-liquid phase-transfer catalysis.

 

Keywords: Sonocatalysis; 1-(prop-2-ynyloxy) benzene; O-propargylation; interfacial reaction; kinetics; MPTC; propargyl bromide ; Phenol.

[1]. G.D. Yadav, Insight into green phase - transfer catalysis, Top. Catal. 29, 2004, 145-161.
[2]. J.C.R. Jarrouse, The influence of quaternary chemicals on the reaction of lPBile hydrogen compounds
and chlorine-substituted derivatives, Hebd. Seances Acad. Sci. Ser. C 232,1951, 1424-1426.
[3]. H.H. Freedman, Industrial application of, Phase transfer catalysis, Past, Present and Future, Pure. Appl.
Chem. 58 ,1986, 857.

 

Paper Type

::

Research Paper

Title

::

Synthesis, Spectral Characterization, In-Vitro Antioxidant and Antimicrobial Studies of Schiff base Copper (II) Complexes

Country

::

India

Authors

::

D. Shakila || A. Dinesh karthik || k. Geetha

Page No.

::

40-48

Paper Index
::
XXXX

A potentially active Schiff base ligand and their binuclear copper complexes have been prepared by the condensation of 2,6-diformyl-4-methyl phenol and 2-aminobenzoic acid in the molar ratio 1:2. The Schiff base ligand can coordinate with two copper ions to form binuclear complexes after the deprotonation of the hydrogen atoms of the phenolic groups in all complexes. The synthesized ligand and its copper(II) complexes were characterized by several techniques using molar conductance, elemental analysis, 1H-NMR, 13C-NMR, UV-Visible, FT-IR and ESR spectral studies. The complexes are non-electrolytic in nature as suggested by molar conductance measurements.............

 

Keywords: Schiff base copper(II) complexes, cyclic voltammetry, antibacterial, antifungal, antioxidant activity.

[1]. A.M. Hamil, M.M. El-ajaily, H.A. Boghdadi, Synthesis, Spectroscopic Investigation and Antibacterial of some New Schiff Base Chelates, International Journal of Chemistry and Applications, 6(1), 2014, 55-62.
[2]. Dr. Mohammed Fakruddin Ali Ahamed, Dr. Venkatesan Jayakumar, Sileshi Tolera Goshu, Synthesis and Characterization Antibacterial Activity of novel ligand-2, 6- diaminopyridine-2-acetyl-5-chlorothiophene and its Metal(II) complexes, World Journal of Pharmaceutical Research, 3(8), 2014, 932-940.
[3]. K. Geetha, M.Nethaji, N.Y.Vasanthacharya, A.R.Chakravarty, Magneto-structural correlation in (μ-alkoxo/hydroxo)(μ-carboxylato)dicopper(II) systems: synthesis, X-ray structure and magnetic properties of aquo (μ-hydroxo)(μ-arylcarboxylato)bis(N,N,N',N'-tetramethylethane1,2-diamine)dicopper(II) diperchlorate, Journal of Co-ord. Chem, 47, 1999, 77-89.
[4]. J.S.Casas, E.E.Castellano, M.D.Couce, J.Ellena, A.Sanchez, J.Sordo, C.Taboada, Zinc(II), cadmium(II) and mercury(II) complexes of the vitamin B1 antagonist oxythiamine, J. Inorg. Biochem, 100, 2006, 124-132.
[5]. J.Angelo, G.Morgant, N.E.Ghermani, D.Desmaele, B.Fraisse, F.Bonhomme, E.Dichi, J.R.J.Sorenson, Crystal structures and physico-chemical properties of Zn(II) and Co(II) tetraaqua(3-nitro-4-hydroxybenzoato) complexes: Their anticonvulsant activities as well as related (5-nitrosalicylato)–metal complexes, Polyhedron, 27, 2008, 537-546

 

Paper Type

::

Research Paper

Title

::

Process Development and Characterization of 2-Aminopyridine Potassium Di-Hydrogen Phosphate Cadmium Chloride (2APKDPC) Crystal

Country

::

India

Authors

::

D. Sivavishnu || R. Srineevasan || J. Johnson

Page No.

::

49-53

Paper Index
::
XXXX

A good optical quality crystal of 2-aminopyridine potassium dihydrogen phosphate cadmium chloride (2APKDPC) was grown by slow evaporation technique at room temperature. The transparent and defect less bulk crystal of 2APKDPC with dimension 23 x 10 x 5 mm3 have been grown by solution growth method in the period of 90 to 95 days. From the single crystal X-ray diffraction study the measured lattice parameters values are a = 7.49 Ǻ, b = 7.49 Ǻ, c = 7.03 Ǻ, α = β = γ = 90º and volume V= 394 Ǻ3, which shows that the grown crystal 2APKDPC belongs to tetragonal crystal system. The crystalline nature of the grown crystal was confirmed by powder X-ray diffraction analysis............

 

Keywords: XRD, FTIR, UV, Optical band gap, Photoluminescence.

[1]. B.B Laud, Lasers and Nonlinear Optics, New age international (P) limited,publishers, New Delhi, 2008.
[2]. K.Thyagarajan, A.K Ghatak, Lasers Theory and Applications, Macmillan Publishers India Limited, Chennai. 12th Edition 2009.
[3]. Bela A. Lengyel ed., Introduction to Laser Physics, John Willey and son's,New York,.1996.
[4]. BreckHitz, J.J Ewing, Jeff Hecht, Introduction to laser technology, IEEEPress, New York
[5]. T.C. SabariGirisun, S. Dhanuskodi, Materials Research Bulletin 45 (2010)pg. no:88–91

 

Paper Type

::

Research Paper

Title

::

Synthesis, Characterization and Anti-Corrosion Studies Of A Pentadentate Ligand and Its Copper (II) Complexes

Country

::

India

Authors

::

Umapathy Chokkanathan || Kannappan Geetha

Page No.

::

54-61

Paper Index
::
XXXX

A pentadentate ligand was synthesized using 4-tertiarybutyl-2,6-bis(chloromethyl) phenol and nicotinic hydrazide. It was characterized by UV-Visible, FT-IR, 1H-NMR, 13C-NMR and mass spectroscopic techniques. The above ligand was coordinated with copper(II) precursors to form corresponding copper (II) complexes. The complexes were characterized by UV-Visible spectra, FT-IR spectra and Conductivity measurements. The anticorrosion activity of the ligand and their complexes were studied.

 

Keywords: 4-tertiarybutyl-2,6-bis(chloromethyl) phenol, Nicotinic hydrazide, Pentadentate ligand, Copper (II) complexes, anticorrosion activity.

[1]. M. M. Antonijevic and M. B. Petrovic, Copper Corrosion Inhibitors. A review, Int. J. Electrochem. Sci., 3 (2008) 1 – 28
[2]. Ngoc Huu Huynh, The Inhibition ofCopper Corrosion inAqueous Environmnets with Heterocyclic Compounds, DOCTOR OF PHILOSOPHY THESIS, QUEENSLANDUNIVERSITY OF TECHNOLOGY SCHOOL OF PHYSICAL SCIENCES, 2004.
[3]. Camila G. Dariva and Alexandre F. Galio, PPEng - CAPES and Universidade Federal do Pampa Bagé/RS, Brazil, Corrosion Inhibitors – Principles, Mechanisms and Applications, Hauppauge, New York : Nova Science Publishers, Inc., [2016], 365 – 379.
[4]. Marija B. Petrović Mihajlović, Milan M. Antonijević, Copper Corrosion Inhibitors. Period 2008-2014. A Review,
[5]. Int. J. Electrochem. Sci., 10 (2015) 1027 – 1053.

 

Paper Type

::

Research Paper

Title

::

Green Synthesis, Characterisation, Corrosion Inhibition and Biological Applications of Schiff Base Transition Metal Complexes

Country

::

India

Authors

::

K. Veni || A. Dinesh Karthik || K. Geetha || D. Shakila

Page No.

::

62-68

Paper Index
::
XXXX

A Schiff base ligand was synthesized from p-chlorobenzaldehyde and o-aminophenol by grinding method. Schiff base transition metal complexes were prepared from the corresponding metal salts in ethanol by grinding method. The synthesized complexes were characterized by UV-Visible, Infra-red, NMR, Mass, ESR spectral techniques and Molar Conductivity studies. Corrosion inhibition of the Schiff base and its metal complexes were evaluated using weight loss method in a 0.1MHNO3 solution for mild steel. It was found that the compounds had a promising inhibitory action against corrosion of mild steel in the medium investigated. The synthesized ligand and its complexes have been screened for antimicrobial studies.

 

Keywords: Schiff base ligand, transition metal complexes, UV-Visible, antimicrobial studies Corrosion inhibition.

[1]. Yasuhiro Inada, Koji Mochizuki, Takashi Tsuchiya, Hiroaki Tsuji, Shigenobu Funahashi, Equilibrium and kinetics of the dinuclear complex formation between N, N'ethylenebis(salicylideneiminato)copper(II) and metal(II,I) ions in acetonitrile, Inorg. Chimica. Acta, 358, 2005, 3009–3014.
[2]. Monica Arora, J.Saravanan, S. Shivaji Bhattacharjee, Synthesis, characterization and antimicrobial activity of some schiff bases of 2-amino-n-(p-acetamidophenyl carboxa, Int J Pharm Pharm Sci, 2013, 5:1.

[3]. C.T.Keerthi Kumar, J.Keshavayya, T.Rajesh,S.K. Peethambar, Synthesis, Characterization and Biological Activity Of Heterocyclic Azo Dyes Derived From 2-Aminobenzothiozole, Int. J. Pharm Pharm Sci, 2013, 5: 1.
[4]. Abd El-Motaleb M. Ramadan, Mohamed M. Ibrahim, Shaban Y. Shaban, Synthesis, characterization, and tyrosinase biomimetic catalytic activity of copper(II) complexes with schiff base ligands derived from a-diketones with 2-methyl-3-amino-(3H)quinazolin-4-one, J. Mol. Struct, 1006, 2011, 348–355.
[5]. P.Viswanathamurthi, K.Natarajan, Ruthenium(II) Carbonyl Complexes Containing Tetradentate Schiff Bases and Their Catalytic Activities, Synth. React. Inorg. Met.-Org. Chem, 36, 2006, 415–418.

 

Paper Type

::

Research Paper

Title

::

Analysis of packed bed adsorption column with nanochitosan /sodium alginate/ microcrystalline cellulose bead for copper (II) removal from aqueous solution

Country

::

India

Authors

::

K. Vijayalakshmi || K.Sangeetha || Dr. P.N. Sudha

Page No.

::

69-78

Paper Index
::
XXXX

In the current research, removal of copper(II) from aqueous solution using nanochitosan/sodium alginate/microcrystalline cellulose bead as an adsorbent is studied in packed bed with respect to various parameters like initial concentration, flow rate and bed height. The breakthrough characteristics of the adsorption were studied by describing the breakthrough curve. The fixed bed column experiments carried out as a function of NCS/SA/MC bed height (1cm and 1.5 cm), flow rate (1.0 ml/min and 1.5 ml/min) and inlet metal ion concentration (200mg/L and 300 mg/L) reveals that the breakthrough time and exhaustion time were increased with increase in bed height and decreased with increasing influent metal ion concentration and flow..........

 

Keywords: Packed bed column, Breakthrough curve, copper (II), Kinetic model, adsorption

[1] S.H.Key, H.J.Jae and K.L.Won, Fixed Bed Adsorption for Bulk Component System, Chemical Engineering Science,50 (5),1995, 813-825 .
[2] Jibesh Datta and Umesh Mishra, Cadmium Removal by Column Study from Aqueous Environment Using Tea Factory Waste as Adsorbent, Journal of chemical biological and physical sciences, 4(3), 2014, 2727-2741.
[3] J.Virkutyte, E.Hullebusch, M.Sillanpee, P. Lens,Copper and trace element fractionation in electrokinetically treated anaerobic granular sludge, Environmental Pollution, 138 (3), 2005, 517–528.
[4] Iman Mobasherpour, Esmail Salahi and Ali Asjodi, Batch and Fixed-Bed Column Performance of Red Mud Adsorbents for Pb(II) Removal, Canadian chemical transactions, 2 (1),2014, 83-96.
[5] Takeshi Gotoh, Keiei Matsushima,Ken-Ichi Kikuchi, Preparation of alginate–chitosan hybrid gel beads and adsorption of divalent metal ions, Chemosphere, 55, 2004, 135–140.