Current-Issue

Volume 7 ~ Issue 12,~Version 1,~December - 2017


Paper Type

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Research Paper

Title

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Screening of Phytochemicals and Isolation of Endophytic Fungi from Medicinal plant Helicteres isora L

Country

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India

Authors

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Gayathri Pai || Chandra M

Page No.

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01-05

Paper Index
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XXXX

The objective of this study was to screen the phytochemicals and isolate the endophytic fungi harbored in the leaf and stem of medicinal plant Helicteres isora L.. Medicinal plants play a key role in traditional medicine and medicinal property is found to be because of phytochemical constituents present in the plants. Phytochemicals such as alkaloids, carbohydrates, tannins, steroids, flavonoids, saponins, terpenoids, coumarins, carboxylic acid, resins, quinone and phenolic compounds were analyzed by using ethanol as solvent. There is a correlation between phytochemicals and secondary metabolites produced by the endophytic fungi. The medicinal plants and their fungal endophytic communities produce similar therapeutic products. The results of the present study showed the presence of secondary metabolites and endophytic fungi such as Penicillium citrinum, Aspergillus niger, Curvularia vermiformis, Rhizopus sp., Cladosporium sp., Alternaria alternata and Fusarium sp., were isolated and identified by morphological characters.

 

Keywords: Endophytic fungi, Helicteres isora L., Phytochemicals, Secondary metabolites.

[1]. Kirthikar,K.R.,Basu,B.D.Indian medicinal plants .National Publishers,Deharadun,1999.pp.371.
[2]. Zhang HW, Song YC, Tan RX. Biology and chemistry of endophytes. Nat Prod Rep 2006;23:753-71.
[3]. Kaul S, Ahmed M, Zargar K, Sharma P, Dhar MK. Prospecting endophytic fungal assemblage of digitalis lanata Ehrh, (foxglove) as a novel source of digoxin: a cardiac glycoside, Biotechnology 2013;3:335-40.
[4]. Sandhu SS, Suneel K, Aharwal RP,Shukla H and Rajak RC. EndophyticFungi: As A Source ofAntimicrobialsBioactive Compounds. World J PharPharmac Sci. 2014a;3(2):1179-1197.
[5]. Strobel G and Daisy B. Bioprospecting for microbial endophytes and their natural products. Microbiol Molecular Biol Rev. 2003;67:491-500.

 

Paper Type

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Research Paper

Title

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Haematological and Biochemical findings of Hair Dye Poisoning

Country

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India

Authors

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Awad Elkareem Abass || Noon mobasher || Fatima Ali || Randah Salah || Nada
Mohamed

Page No.

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06-10

Paper Index
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XXXX

Background/aim: Hair dye containing paraphenylenediamine (PPD) is commonly used in Sudan as
cosmetic agent. The direct toxic effect of PPD can lead to many pathological problems. Therefore, present study aimed to investigate some hematological and biochemical parameters in Sudanese who exposed to hair dye poisoning. Patients/methods: A cross sectional hospital -based study was conducted in Ear-Nose-Throat (ENT) Hospital- Khartoum, 30 PPD- poisoned patients who were admitted for clinical management were enrolled in the study. Clinical manifestations were examined by clinician in the Hospital. Full blood count, renal function tests, and liver function tests were performed for each patient.............

 

Keywords: Hair dye, investigation, Laboratory, Poisoning, PPD, Signs.

[1]. Sampathkumar K, Sooraj YS, Mahaldar AR, Ajeshhkumar RP, Muthiah R. Hair dye poisoning: An emerging threat. Indian J Crit Care Med, 11, 2007, 212-214.
[2]. Ayoub Filali, I. Semlali, V. Ottaviano, C. Furnari, Danilo Corradini, Rachida Soulaymani. A
retrospective study of acute systemic poisoning of paraphenylenediamine (occidental takawt) in
Morocco. Afr J Tradit Complement Altern Med, 39, 2006, 142–149.
[3]. Suliman SM, Fadlalla M, Nasr Mel M, et al. Poisoning with hair-dye containing paraphylene diamine: ten years experience. Saudi J Kidney Dis Transpl, 6, 1995, 286–289.
[4]. Kallel H, Chelly H, Dammak H, et al. Clinical manifestations of systemic paraphenylene diamine
intoxication. J Nephrol, 18, 2005, 308–311.
[5]. Ashar A. Acute angioedema in paraphenalinediamine poisoning. J Pak Med Assoc, 53, 2003, 120-122.

 

Paper Type

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Research Paper

Title

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Volumetric and Acoustical Study of Antimalarial Hydroxychloroquine Sulfate Drug in DMSO-Water mixtures at different temperatures

Country

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India

Authors

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Shweta Pendse || H G Jahagirdar || MKN Yenkie

Page No.

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11-19

Paper Index
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XXXX

The densities and speeds of sound have been measured for ternery mixtures of hydroxychloroquine sulfate in aqueous-dimethyl sulfoxide(DMSO) mixtures at 20 vol% interval of the cosolvent at 303.15, 308.15 and 313.15 K and frequency 2MHz. The experimental data has been used to determine various acoustic/thermodynamic parameters viz. isentropic compressibility ( ks), intermolecular free length (Lf), relative association (RA) and specific acoustic impedance (Z). The changes in these properties with composition and temperature are used to interpret the nature of solute-solvent, solute- solute interactions in the system.

 

Keywords: Acoustical properties, Antimalarial, DMSO, Molecular interactions, Ultrasonic velocity

[1]. Marcus Y., Solvent mixtures: properties and selective salvation (Marcel Dekker: New York (NY); 2002)
[2]. A. Awasthi, A. Awasthi, Acoustic, volumetric, and spectroscopic studies of formamide with 2-alkoxyethanols at different temperatures. J Chem Thermodyn.,53, 2012, 144–151
[3]. A. Awasthi, A. Awasthi, Intermolecular interactions in formamide + 2-alkoxyethanols: viscometric study, Thermochimica Acta.,537, 2012, 57–64.
[4]. A. Awasthi, A. Awasthi, Intermolecular interaction in binary mixtures of formamide with 2-alkoxyethanol at different temperatures: optical and internal pressure study, Phys Chem Liqs., 51, 2013, 112–123.
[5]. A. Awasthi, Tripathi BS, A. Awasthi, Applicability of corresponding-states group-contribution methods for the estimation of surface tension of multicomponent liquid mixtures at 298.15 K, Fluid Phase Equilibria, 287, 2010, 151–154.

 

Paper Type

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Research Paper

Title

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Prevalence of Gastrointestinal Tract Cancer Cases among Population of Tripura: A Histological Study

Country

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India

Authors

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Asis Debbarma || Arup Bhaumik || Biswajit Chowdhury || Payel Chakraborty || Souvik Ghatak || Sandeep Roy Sarkar

Page No.

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20-23

Paper Index
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XXXX

Histochemistry is currently the widely used methodology for recognition of gastrointestinal tract (GI tract) cancers like stomach, rectum, colon and oesophagus. Limited studies have addressed the prevalence of GI tract malignancies in Tripura. The objectives of this study were to find out the prevalence of gastrointestinal tract cancers among the population of Tripura, located in North-Eastern part of India. Accordingly, a hospital based study was carried out to evaluate the histopathological aspects of gastrointestinal tract cancer patients attending to Agartala Govt. Medical College during the period of 2010-2017. In this study 161 cases of GI cancers belonging to age between 5 to 85 years were found positive out of total 187 suspected samples. The present study demonstrates.............

 

Keywords: GI tract cancer, Histology, Haematoxylin and eosin stain, Tripura.

[1]. Report on Causes of Death in India 2001-03, Office of Registrar General, India, New Delhi. 2009. Available from: URL:http://censusindia.gov.in/Vital_Statistics/Summary_Report_Death_01_03.pdf. Accessed September 24, 2017.
[2]. J. Ferlay, I. Soerjomataram, R. Dikshit, S. Eser, C. Mathers, M. Rebelo, et. al, Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. International Journal of Cancer, 136, 2015, 359–86.
[3]. S. Ghatak, P. Chakraborty, S.R. Sarkar, B. Chowdhury, A. Bhaumik, and N.S. Kumar, Novel APC gene mutations associated with protein alterations in diffuse type gastric cancer. BMC Medical Genetics, 18, 2017, 61.
[4]. N.S. Ghadyalpatil, S. Chopra, P. Patil, A. Dsouza, A. Saklani. Gastrointestinal cancers in India: Treatment perspective, South Asian Journal of Cancer, 5(3), 2016, 126–136.
[5]. A. Sharma, Gastrointestinal cancers in India: Treatment perspective, South Asian Journal of Cancer, 5(3), 2016, 125–126.