March - 2020 (Volume-10 ~ Issue-3 ~ Series-1)

Paper Type

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Research Paper

Title

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Pharmacological potential of Orchis mascula- A review

Country

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Iraq

Authors

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Ali Esmail Al-Snafi

Page No.

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01-06

Orchis mascula was used traditionally as astringent, demulcent, expectorant, nutritive, restorative, invigorator and sexual tonic. In addition to its aphrodisiac effect, it was also used in the treatment of male sexual disorders like erectile dysfunction and impotence, and also as a nervine tonic that to treat stress and mental disorders. Orchis mascula contained alkaloids, saponins, tannins, phenolics, terpenes, sterols and flavonoids. The pharmacological studies showed that Orchis mascula possessed cardiovascular, hypolipidemic, antioxidant, antiepileptic, DNA protective, antimicrobial, cytotoxic, aphrodisiac, smooth muscle relaxant, and many other effects. The current review was designed to shed some light on the chemical constituents and pharmacological effects of Orchis mascula.

 

Keywords: constituents, pharmacological effects, Orchis mascula

[1]. Al-Snafi AE. Chemical constituents and pharmacological effects of Lythrum salicaria - A review. IOSR Journal of Pharmacy 2019; 9(6): 51-59.
[2]. Al-Snafi AE. Medical benefit of Malva neglecta - A review. IOSR Journal of Pharmacy 2019; 9(6): 60-67.
[3]. Al-Snafi AE. A review on Lagerstroemia indica: A potential medicinal plant. IOSR Journal of Pharmacy 2019; 9(6): 36-42.

[4]. Al-Snafi AE. Chemical constituents and pharmacological effects of Lathyrus sativus- A review. IOSR Journal of Pharmacy 2019; 9(6): 51-58.
[5]. Al-Snai AE. A review on Lycopus europaeus: A potential medicinal plant. IOSR Journal of Pharmacy 2019; 9(7): 80-88.

 

Paper Type

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Research Paper

Title

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Constituents and pharmacology of Onopordum acanthium

Country

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Iraq

Authors

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Ali Esmail Al-Snafi

Page No.

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07-14

Onopordum acanthium was used traditionally as bactericide, cardiotonic and hemostatic, diuretic, to treat nervousness, as antitumor agents and for the treatment of inflammation of the bladder and the respiratory and urinary systems. It contained saponins, alkaloids, sesquiterpen lactones, flavonoids, triterpenes, sterols, nitrogen-containing compounds, phenolic acids, coumarins, inulin, soluble sugars, proteins and oils. The pharmacological studies showed that Onopordum acanthium possessed antibacterial, antioxidant, anticancer, antiinflammatory, analgesic, antipyretic, hypotensive, antiepileptic, wound healing, xanthine oxidase and ACE inhibitory effects. The current review highlighted the chemical constituents, therapeutic and pharmacological effects of Onopordum acanthium.

 

Keywords: constituents, pharmacology, therapeutic effects, Onopordum acanthium

[1]. Al-Snafi AE. Chemical constituents and pharmacological activities of Lantana camara- A review. Asian J Pharm Clin Res 2019; 12912):10-20.
[2]. Al-Snafi AE. Chemical constituents and pharmacological effects of Lepidium sativum- A review. International Journal of Current Pharmaceutical Research 2019; 11(6):1-10.
[3]. Al-Snafi AE. Constituents and pharmacology of Fumaria officinalis- A review. IOSR Journal of Pharmacy 2020; 10(1):17-25.
[4]. Al-Snafi AE. Chemical constituents and pharmacological effects of Melilotus Officinalis- A review. IOSR Journal of Pharmacy 2020; 10(1):26-36.

 

Paper Type

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Research Paper

Title

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Phytochemical Analysis, Antibacterial and Antioxidant Activity Study of elettaria Cardamomumseed

Country

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Malaysia

Authors

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Loh Kok Shen || Nabila Perveen || Naeem Hasan Khan

Page No.

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15-32

To evaluate the phytochemical constituents, antimicrobial and antioxidant scavenging activity of ethanolic Soxhlet and maceration extracts. In present research, soxhlet extraction and maceration extractions were applied to the seed of Elettaria Cardamomumby using absolute ethanol.Phytochemical analysis for the important chemical constituents from ethanolic extract were carried out.Antimicrobial activity of Elettaria Cardamomumextract was carried out using well diffusion method on the Nutrientagar.Antioxidant activity of Elettaria Cardamomumwas carried out using total phenolic content test and DPPH to identify the percentage of scavenging by the chemical constituents. For phytochemical analysis, only test for alkaloids, test for reducing sugar, test for saponin, test for salkowski'test and test for carbohydrates that showed positive results.For antibacterial screening, all the concentrations.........

 

Keywords: Soxhlet, maceration, antibacterial, antioxidant, phytochemical.

[1]. Kubo I, Himejima M, Muroi H. Antimicrobial Activity of Flavor Components of Cardamom Elattaria cardamomum (Zingiberaceae) Seed. J Agric Food Chem. 1991.
[2]. Teneva D, Denkova Z, Goranov B, Denkova R, Kostov G, Atanasova T, et al. Chemical Composition and Antimicrobial Activity of Essential Oils from Black Pepper, Cumin, Coriander and Cardamom Against Some Pathogenic Microorganisms. Acta Univ Cibiniensis Ser E Food Technol. 2016.
[3]. Gupta M. Pharmacological properties and traditional therapeutic uses of important indian spices: A review. Int J Food Prop. 2010.
[4]. Spice Pages: Cardamom Seeds (Elettaria cardamomum) [Internet]. [cited 2019 May 14].
[5]. Elettaria cardamomum (fruit) - AHPA Botanical Identity References Compendium [Internet]. [cited 2019 May 14].

 

Paper Type

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Research Paper

Title

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A Prospective Observational Study on Evaluation of Effectiveness of Monotherapy and Combinational Therapy in Epilepsy Patients

Country

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India

Authors

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B. Raja Narender || Dr. Thatikonda Anil Kumar || Ayesha Zeba || Gotte Priyanka || Sadaf Sultana

Page No.

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33-43

Background: Epilepsy is a central nervous system (neurological) disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behaviour, sensations, and sometimes loss of awareness. (1) By definition, epilepsy requires typically two unprovoked seizures, separated by greater than 24 hours. (2) In the past epilepsy was considered as the sacred disease in support of this view a large number of people believed that epilepsy affected people who to some extent taken hold of by demons or that the visions experienced by the epileptic people were sent by the Gods. Material and Methods: It is a prospective observational study on effectiveness of monotherapy and combinational therapy of Anti-epileptic drugs in different age groups of patients. Patients diagnosed with Epilepsy can be prescribed with single AED and combination of AED mainly on the type of epilepsy were included in our study. Our study includes............

 

Keywords: Epilepsy, Anti-Epileptic Drug, Monotherapy, Combinational Therapy, Medication Adherence

[1]. Fisher RS, van Emde Boas W, Blume W, Elger C, Genton P, et al. (2005) Epileptic seizures and epilepsy: definitions proposed by the International League against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia 46: 470-472. [2]. Harrison R, Daniel H and Lowenstein. Harrison's Principles of Internal Medicine. 16th edition.
[3]. Robert S. Fisher, MD, PhD Maslah Saul MD Professor of Neurology Director, Stanford Epilepsy Centre: The Definition of Epilepsy.
[4]. P.A. Dekker, M.D.† Epilepsy: A manual for Medical and Clinical Officers In Africa
[5]. Oxford English Dictionary. Retrieved 8 September 2009.