April - 2021 (Volume-11 ~ Issue-4 ~ Series-1)

Paper Type

::

Research Paper

Title

::

An ACE-based boisson (Elder tree syrup) enbodies a draconian remedy to prevent and combat seasonal flus and covid symptoms

Country

::

 

Authors

::

Franco Deraco || Lorenzo Martini

Page No.

::

01-05

In occasion of the dramatic advent of Coranavirudae and its variants in the World, during the winter 2020-2021, few have been the physicians who have supposed that manifold symptoms were evoked by 4 strains of seasonal flu from South America or Asia and asserted that the patients were infected by covid.The AA have focuse their attention on a panel group of 6 young workers who manifested odd symptoms, that could be caused by flu or by covid (these strangers did not have Healf Insurance Fund in our land).The AA have tried to cure these volunteers administering them an alder tree soft drink added with three vitamins, that correspond to the famous acronym ACE.Symtoms tend to disappear at all after 6 days of treatment.

 

KEYWORDS: A/Guangdong-Maonan/SWL 1536/2019 [H1N1] pdm09-like, A/Hong Kong/2671/2019 [H3N2]-like, B/Washington/02/2019 [B/Victoria lineage]-like), B/Phuket/3073/2013 [B/Yamagata lineage]-like), Elder tree syrup, Vitamin D.

[1]. The Lancet Diabets & Endocrinology, 9 (21)
[2]. Anderson K.E. et al., Adv. Clin. Chem., 1976, 18, 247.
[3]. Blomhoff R. et al., Science, 1990, 250 (4979), 399.
[4]. Clagett-Dame M., DeLuca H.F., Annu. Rev. Nutr., 2002, 22, 347.
[5]. D'Ambrosio D.N. et al., Nutrients., 2011, 3 (1), 63.


Paper Type

::

Research Paper

Title

::

Public Knowledge, Attitudes, Practices and Assessment of Side Effects and Effectiveness of Covid Vaccine: An Online Cross Sectional Survey in Gujarat

Country

::

India

Authors

::

Dr. Khushbu S. Patel || Dr. Akruti S. Khodakiya || Dr. Ketan P. Patel

Page No.

::

06-13

Background: Recently, billion of people are suffering from COVID-19 pandemic era since last one year. Safe and effective vaccines will be a game changer: but for the predictable future we must carry on wearing masks, physically and social distancing and avoiding crowds. Aim: Aim and objective of research is to survey the effectiveness and side effects of covid vaccine and also what to be a public knowledge, attitudes and practices towards the covid vaccine in corona pandemic era. Methods: A cross sectional survey was conducted within the duration of March 2021 to April 2021 by using qualitative research approach and surveying public knowledge, attitudes, practices and assessment of side effects and effectiveness of covid vaccine. Among the 1000 people were included study from Gujarat, the respondents..........

 

KEYWORDS: Vaccine, Corona, Side effects, Effectiveness, Gujarat.

[1]. Gates B. Responding to Covid-19—A Once-in-a-Century Pandemic? N. Engl. J. Med. 2020; 382: 1677–1679.
[2]. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/covid-19-vaccines.
[3]. Lumley et alAntibody status and incidence of SARS-CoV-2 infection in health care workers. N Engl J Med . 2020; DOI: 10.1056/NEJMoa2034545.
[4]. Polack et al. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. N Engl J Med. 2020; 383: 2603–2615.
[5]. Tan WT, Lu Y, Zhang J, et al. Viral Kinetics and Antibody Responses in Patients with COVID-19. medRxiv 2020.


Paper Type

::

Research Paper

Title

::

Pancreatic β- cell Effects of Canagliflozin versus Vildagliptin on Streptozotocin-Induced Type 2 Diabetes Mellitus in Male Albino Rats

Country

::

Egypt

Authors

::

Tarteel Youssef Hassan Mohamed || Mohamed Abdelhafeez Ahmed || Shireen S. Mahmoud

Page No.

::

14-21

Background: Diabetes mellitus (DM) is a chronic illness characterized by an elevated blood glucose associated with absent or inadequate pancreatic insulin secretion, with or without concurrent impairment of insulin action. Aim: This study aimed to compare the pancreatic β-cell function improvement by DPP-4 inhibitors as Vildagliptin and SGLT2 inhibitors as Canagliflozin on diabetic male albino rats. Methods: Thirty-six rats were randomly divided into 4 equal groups (n=9): control group, untreated diabetic group, vildagliptin-treated diabetic group (20 mg/kg/day by orally) and canagliflozin-treated diabetic group (40 mg/kg/day orally). Type 2 DM was induced by intraperitoneal(IP) injection of nicotinamide (230 mg/kg) 15 min prior to single dose injection of streptozotocin (60 mg/kg, I.P.). The assessed parameters were fasting blood glucose (FBG), proinsulin, insulin, proinsulin/Insulin ratio, relative expression of MafA gene (β-cells specific transcription factor), Pancreatic and duodenal homebox-1 (PDX-1) gene and histopathology for pancreatic β- cell...........

 

KEYWORDS: Diabetes mellitus, Vildagliptin, Canagliflozin, Insulin.

[1]. Muñoz-Torres AV, Medina-Bravo P, Valerio-Pérez BE, Mendoza-Salmeron G, Escobedo-de la Peña J, Velázquez-López L. Positive health beliefs are associated with improvement of glycated hemoglobin and lipid profiles in Mexican patients with type 2 diabetes mellitus: a cross-sectional study. BMC Public Health 2020; 20(1):761.
[2]. Barret KE, Boitano S, Barman SM. Ganong's review of medical physiology (24th ed.). McGraw-Hill Medical. ISBN 2012; 978-0-07-178003-2.
[3]. He YL. Clinical pharmacokinetics and pharmacodynamics of vildagliptin. Clinical pharmacokinetics 2012; 51(3):147-62.
[4]. Elkinson S, Scott LJ. Canagliflozin: first global approval. Drugs 2013; 73(9):979-88.
[5]. Plosker GL. Canagliflozin: a review of its use in patients with type 2 diabetes mellitus. Drugs 2014; 74(7):807-24.


Paper Type

::

Research Paper

Title

::

Evaluation of Phytochemical and Proximate Composition of Garcinia Kola Seeds and Vernonia Amygdalina Leaves Sold In Abuja

Country

::

Nigeria

Authors

::

Onwuliri E. A. || Opara J. K. || Agumah N. B. || Onwuliri F. C || Oru C. M. || Njoku M.

Page No.

::

22-28

This study was aimed at evaluating the phytochemical and proximate composition of Garcinia kola (Bitter kola) seeds and Vernonia amygdalina (Bitter leaf) sold in Abuja, Nigeria. Bitter leaf and bitter kola were collected from various markets in Abuja. Some of the bitter leaves were collected from various gardens as bitter leaf widely grows in most parts of Nigeria. In evaluation of phytochemical constituents, Flavonoids and Saponins were the most abundant in both G. kola and V. amygdalina (4.54 ±0.35: 6.07 ±6.05) mg/100g. Flavonoid contents of G. kola (3.62 ±2.54) mg/100g and V. amygdalina (21.04 ±9.72) mg/100g represented the highest phytochemical contents. There was, however, no significant difference (p > 0.05) in the Saponins and Flavonoids content of G. kola and V. amygdalina: Cal...........

 

KEYWORDS: PHYTOCHEMICAL, VITAMINS, GARCINIA, VERNONIA, ABUJA, NIGERIA.

[1]. Adegboye, M.F., Akinpelu, D.A. and Okoh, A. (2008). The bioactive and phytochemical properties of Garcinia kola (Heckel) seed extract on some pathogens. African Journal of Biotechnology, 7(21): 3934-3938.
[2]. Adesuyi, A.O. Elumm, I.K. Adaramola, F.B. and NwokochaA. G.M. (2012).
[3]. Nutritional and Phytochemical Screening of Garcinia kola. Advance Journal of Food Science and Technology. 4(1): 9-14
[4]. Almagoul, A.Z., Bashir, A.L., Farouk, A. and Salih, M. (1985). Antimicrobial activity of certain Sudanese plants used in folkloric medicine. Fitoterapia, 6: 331-1985.
[5]. Asaolu, S. S., Adefemi, O. S., Oyakilome, I. G., Ajibulu, K. E. and Asaolu, M. F. (2012). Proximate and mineral composition of Nigerian leafy vegetables. Journal of Food Research, 1: 214-218.


Paper Type

::

Research Paper

Title

::

Pharmacists Are Able To Give Best Treat and Care For Coronaviruses Patients

Country

::

 

Authors

::

Dr.Niranjan Sutar || Ranju Sutar || Poulami Sen

Page No.

::

29-38

As the number of confirmed cases and deaths attributed to COVID-19 continue to climb worldwide, policymakers should act quickly to respond. As state policymakers take steps to ensure that their communities are prepared for COVID-19, they should evaluate their state's laws and emergency plans to ensure that pharmacists practicing in hospitals, clinics, physician offices and retail settings are able to effectively support the COVID-19 response. In many communities, pharmacists are the most accessible healthcare providers and the first touch point of patient engagement with the healthcare system. In fact, 90% of all Americans live within five miles of a community pharmacy. In rural and underserved communities and in areas experiencing physician shortages, pharmacists may be the only healthcare provider that is immediately...........

 

KEYWORDS: Corona virus, COVID-19, Pharmaceutical care, Pharmacists, Pharmacy service and Public health.

[1]. Han Q, Lin Q, Jin S, You L. Recent insights into 2019-nCoV: a brief but comprehensive review. J Infect. 2020. https ://doi. org/10.1016/j.jinf.2020.02.010 (Epub ahead to print).
[2]. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel corona virus from patients with pneumonia in China, 2019. N Engl J Med. 2020; 382:727–33.
[3]. WHO Corona virus Disease 2019 (COVID-19) Situation Report-52. https ://www.who.int/docs/defau lt-sourc e/coron aviru se/20200 312-sitre p-52-covid -19.pdf?sfvrs n=e2bfc 9c0_2.Accessed 12 Mar 2020.
[4]. Press release UK Government (April 2, 2020) £300 million announced for community pharmacies to support them during corona virus outbreak, Available on: https://www.gov.uk/government/news/300-millionannounced-for-community-pharmacies-to-support-them-during-coronavirusoutbreak.Accessed 05 April 2020.
[5]. Rutter V, Chan AHY, Tuck C, Bader L, Babar Z-U-D, Bates I. Weaving the health and pharmaceutical care agenda through the themes of the commonwealth heads of government meeting (CHOGM), London 2018. J Pharm Policy Pract. 2018;11(1):10.


Paper Type

::

Research Paper

Title

::

L'amidon De Manioc Dans La Formulation Des Comprimes.

Country

::

Cote d'Ivoire

Authors

::

DJOKO Ernest || NGANTCHOUKO Beranger || MEZAZEM T. Urbain || KOFFI Armand

Page No.

::

40-54

Introduction : L'amidon est un polyoside du glucose que l'on retrouve dans de nombreuses graines et tubercules. Les plantes riches en amidon sont largement utilisées dans l'alimentation et l'industrie alimentaire. L'industrie pharmaceutique a retenu, pour la fabrication des médicaments, les amidons de blé, de riz, de maïs et de pomme de terre. Les tubercules de manioc, également très riches en amidon, sont largement utilisés dans l'alimentation. Nous nous sommes donnés comme objectif dans la présente étude, d'évaluer la capacité de l'amidon de manioc produit au Cameroun à se substituer aux autres amidons dans la fabrication des comprimés. Matériel et méthodes : L'amidon a été extrait de deux...........

 

KEYWORDS: amidon, excipient, comprimés

[1]. Tinamri M, Lagmi I. Optimisation des conditions d'extraction des polysaccharides issus d'Astragalus gombo bunge (Fabaceae) récolté au Sahara septentrional Est algérien [Thèse de doctorat :Phar].Algérie :Université Kasdi Merbah Ouargla.2014
[2]. Mbougueng PD. Influence des amidons natifs ou acétylés de manioc et de pomme de terre sur les propriétés physico-chimiques et texturales du pâté de Boeuf (Bos indicus) [Thèse de doctorat]: Vandoeuvre-les-Nancy, INPL; 2009
[3]. Kouassi Atse Cedric Alain Junior docteur. Etude comparative des caractéristiques galéniques et biopharmaceutiques des comprimés de paracétamol à base d'amidon d'igname Krenglè et Kponan, de taro rouge et blanc et des comprimés de « paracétamol spécialité et son générique. [mali: Phar] : BAMAKO; 2009.
[4]. Conseil de l'Europe. Pharmacopée européenne 6ème Édition, Volumes 1 à 2 Volume 50 de European treaty series Numéro 50 de Série des traités européens. 6ème éd. Conseil de l'Europe, 2007; 2008
[5]. Burrell M. Starch: the need for improved quality or quantity—an overview. Journal of Experimental Botany. 2003; 54(382):451-6.