Volume 8 ~ Issue 8,~Version 1, ~ August - 2018


Paper Type

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Research Paper

Title

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Microbiota and LPS-induced obesity inflammation: therapeutic implications

Country

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Italy

Authors

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Raffaela Pero || Giovanna Fico || Barbara Lombardo || Olga Scudiero || Sonia Laneri

Page No.

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01-12

Paper Index
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XXXX

Obesity and chronic low-grade inflammation are becoming global epidemics. The dysbiosis has a specific role in the metabolism and energy stocks of the host. The discovery that a low-grade of inflammation could be directly connected to the intestinal microbiota metabolic endotoxemia (elevated levels of plasma lipopolysaccharides) has allowed the identification of novel mechanisms involved in the control of the intestinal barrier. In this review, it will analyze the latest news to explain how human symbiotic microorganisms participate in the growth of the fat reserves and promote insulin resistance as a low-grade inflammation. Besides, it will discuss new treatments with probiotics and prebiotics as a promising therapeutic approach to reverse the host's metabolic changes linked to dysbiosis observed in obesity.

 

Keywords: LPS, microbiota, inflammation, intestinal permeability, obesity.

[1]. Ali KF, Shukla AP, Aronne LJ (2016) Bupropion-SR plus naltrexone-SR for the treatment of mild-to-moderate obesity. Expert Rev Clin Pharmacol 1:27-34
[2]. Armougom F, Henry M, Vialettes B, Raccah D, Raoult D (2009) Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients. PLoS ONE 4: e7125
[3]. Ayabe T, Satchell DP, Wilson CL, Parks WC, Selsted ME, Ouellette AJ (2000) Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nat Immunol 1: 113-118
[4]. Bäckhed F, Ding H, Wang T, Hooper LV, Koh GY, Nagy A (2004) The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A 101:15718–15723
[5]. Bäckhed F, Manchester JK, Semenkovich CF, Gordon JI (2007) Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci U S A 3:979-984 Bevins CL, Salzman NH (2011) Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis. Nat Rev Microbiol 9: 356–368

 

Paper Type

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Research Paper

Title

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The Isolation and Selection of Lactobacillus Sp. Can Inhibite Helicobacter Pylori

Country

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Vietnam

Authors

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Dang Dinh Hiep

Page No.

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13-17

Paper Index
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XXXX

In this newspaper, we want to isolate Lactobacillus sp. which have the ability to inhibite H.pylori. As a result, 20 lactic strains are isolated from fermented food and choose a strain from 20 strains has the biggest inhibition with H.pylori . In adittion, selecting strain is determined Lactobacillus plantarum by 16S rDNA and its inhibition with H.pylori is the strongest (the rate percent of inhibition is 70.48%). Then, L.plantarum is used to create bioproduct by miniB 290 and some parameters are determined: the input temperature is 1000C, the rate of input pump is 5 ml/min.

 

Keywords: Helicobacter pylori, inhibition, Lactobacillus plantarum, lactic strains, fermented food.

[1]. Ta Long et al (2010), "Helicobacter pylori infection, peptic ulcer and gastric cancer in Vietnam", Vietnam Journal of Biotechnology 5(20), 1317-1334.

[2]. Bahremand S, Nematollahi LR, Fourutan H et al. (2006), "Evaluation of triple and quadruple Helicobacter pylori eradication therapies in Iranian children: a randomized clinical trial", Eur J Gastroenterol Hepatol. 18(5), pp. 511-514.

[3]. Frank J. C and Nino M (2002), "The Lactic Acid Bacteria". Microbiology, vol 28, pp. 281-370.

[4]. Do Thi Bich Thuy, Phan Thi Be, Tran Thi Ai Luyen, (2013). "Study on properties of Lactobacillus plantarum DC2 isolated from traditional lactic fermented product Dua Cai" in Hue City, Vietnam. Journal of Biotechnology, 11(1): 145-152.

[5]. Aiba, Y., N. Suzuki, A. M. Kabir, A. Takagi, and Y. Koga. 1998. "Lactic acid-mediated suppression of Helicobacter pylori by the oral administration of Lactobacillus

 

Paper Type

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Research Paper

Title

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Acute And Chronic Toxicity Effects Of 2, 6-Bis (2, 5-Dimethoxybenzy-Lidene)Cyclohexanone (Bdmc33) In Zebrafish (Daniorerio) Tested On Adulthood Life Stage

Country

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Nigeria

Authors

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Ndatsu Yakubu || Syahida Ahmad || Hamzat Usman Boko || Hassana Abubakar || Amuzat O. Aliyu

Page No.

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18-27

Paper Index
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XXXX

The toxicity effects of 2,6-bis(2,5-dimethoxybenzy-lidene)cyclohexanone (BDMC33)on adult zebrafish (>6 months old) was investigated in this study. The acute and subchronic toxicity tests by exposing adult zebrafish (>6 months old) to various concentrations of BDMC33 for 48 hrs and 14 days, respectively, were conducted. The 48 hrs LC50 value was determined, mean weight, malondialdehyde (MDA) and myeloperoxidase (MPO) activities, and the pathological changes in the intestine and liver of treated zebrafish were evaluated after 14 days of exposure. Similar analyzes on aspirin (positive control) and 3-(2-Fluoro-benzylidene)-5-(2-fluorocyclohexylmethylene)-piperidin-4-one (EF-24)(check control) were also examined for comparison. The 48 hrs LC50 values were 8 μM (aspirin), 10 μM (EF-24), and 20 μM (BDMC33). The average weights at 14 days were 0.87 mg (aspirin), 1.89 mg (EF-24), and 2.01mg (BDMC33)............

 

Keywords: Acute toxicity; BDMC3; chronic toxicity; curcumin analogues; zebrafish.

[1]. OECD(2006). "OECD draft proposal for a new guideline, 1st version. Guideline for the testing of chemicals. Fish Embryo Toxicity", FET Test, 2006.
[2]. Jevgenij, A., Kovrižnych. R.S., Dagmar, Z.,.Aweta, R.S., Soňa, W. (2013). "Acute toxicity of 31 different nanoparticles to zebrafish (Daniorerio) tested in adulthood and in early life stages – comparative study," Interdisciplinary Toxicology, 6(2): 67–73.
[3]. OECD, 203. (1992). "Fish, Acute Toxicity Testing of Chemicals". OECD 203, 1992: 9
[4]. Olson, H., Betton, G., Robinson, D.,.Thomas, K., Monro, A., Kolaja, G., Lilly, P., Sanders, J., Sipes, G., Bracken, W., Dorato, M., Deun, K.V., Smith, P., Berger, B., Heller, A. (2000)."Concordance of toxicity of pharmaceuticals in humans and in animals", Regulatory Toxicology and Pharmacology, 32: 56–67.

[5]. Postlethwait, J.H., Woods, I.G., Ngo-Hazelet,t P., Yan, Y.L., Kelly, P.D., Chu, F., Talbot, W.S. (2000). "Zebrafish comparative genomics and the origins of vertebrate chromosomes" Genome research, 10(12): 1890-1902.

 

Paper Type

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Research Paper

Title

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Effect Of Heavy Metals Hgcl2 And Cdcl2 On Glycogen Activity Of Bivalve Lamellidens Marginalis…..

Country

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India

Authors

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Sandhya M. Sonawane || Mayur Sonawane

Page No.

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28-35

Paper Index
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XXXX

Heavy metal and pesticide pollutants cause stress to the aquatic organism and change its metabolic activity. The heavy metal pollutants give rise to alterations in the metabolic and physiological activity both after short and long term exposures. To investigate the physiological changes after pesticide and heavy metal treatment the most fundamental one would be the study of change in the biochemical constituents. Carbohydrates, proteins and lipids are the important metabolites which provide energy to different vital processes. They glycogen content in freshwater bivalve, L. marginalis was altered indicating the effects of heavy metals. The average glycogen content in acute and chronic treatment by heavy metal HgCl2 and CdCl2 was decreased in the whole body. The depletion of glycogen content was greater in the digestive gland as compared to the foot and mantle of the bivalve, when exposed to pollutants..............

 

Keywords: Heavy metals HgCl2 and CdCl2, L. marginalis, Glycogen, digestive gland, acute, chronic.

[1]. Abel, P.D. (1974) : Toxicity of synthetic detergent to fish and aquatic vertebrates. J. Fish. Biol., 6 : 279-298.
[2]. Banerjee, S.K. and Ghosh, S.D. (1978) : Toxicity of cadmium : A comparative study in the air breathing fish Clarius bactrachus (Linn.) and in the non air breathing one, Tilapia mossambica (Peters). Ind. J. Exp. Biol., 16 : 1274.
[3]. Banerjee, S.K., Dastidar, S.G., Mukhopadhya, P.K. and Dehadari, P.V. (1978) : Toxicity of cadmium : A comparative study in air breathing fish, Clarius batrachus (Linn.) and in non air breathing one Tilapia mossambica (Peters), Indian J. Exp. Biol., 16 : 1274-1277.
[4]. Barnes, H. and J. Blackstoch, (1973): Stimation of lipids in marine animals and tissues. Detailed investigation of the sulphophosphovanilin method for total lipids. J. Exp. Mar. Biol. Ecol., 12 : 103-118.
[5]. Bhagalakshmi, A. (1981): Physiological studies on the fresh water field crab, Oziotelphusa (Paratelphusa) senex senex (Fabricus) in relation to impact. Ph.D. thesis, Shri Venkateshwara University, Tirupati, A.P., India.

 

Paper Type

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Research Paper

Title

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Assessing Students Knowledge on the Use of NSAIDs at Lusaka Apex Medical University

Country

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Zambia

Authors

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Amina Ravalia || Yassa Yoniene Pierre || Amina Dilmohamed

Page No.

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36-44

Paper Index
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XXXX

Self-medication is a common problem worldwide and is defined as the use of non-prescription drugs without supervision of a physician for the treatment of self diagnosed disorders or symptoms and might become a serious health problem(Mooataz et al., 2016; Barbara et al., 2015; Fariba et al., 2014; Girma et al., 2011). It is influenced by various factors such as education, family, society, law, availability of drugs and exposure to advertisements(Mooataz et al., 2016; Gupta et al., 2013; Girma et al., 2011). Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of medications used in the treatment of pain, inflammation, and fever. These medications are common, affordable, easy to access and hence they are commonly used for treating injuries and for general pain management (Safila et al., 2014; Gupta et al., 2013; Sonia et al., 2013; Girma et al., 2011; Awad et al., 2005).

[1]. Awad A, Eltayeb I, Matowe L, Thalib L, 2005. Self medication with antibiotics and antimalarials in the community of Khartoum State, Sudan. Journal of Pharmacy and Pharmaceutical Science 2005, Vol 8 (2), pp. 326-331.
[2]. Barbara Kołłątaj, Magda Sowa, Witold Kołłątaj, Piotr Książek, Justyna Szakuła, 2015. The impact of medical knowledge on attitudes towards the use of OTC drugs. Polish Journal of Public Health, 125(3), pp. 137-143.

 

Paper Type

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Research Paper

Title

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Determination of Fluorides and Exposure of Children to Intake from Toothpaste and Mouthwash

Country

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Bosnia And Herzegovina

Authors

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Pazalja M. || Salihović M. || Ţiga N. || Alagić-Dţambić L. || Pašić- Kulenović M

Page No.

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45-50

Paper Index
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XXXX

Fluorides are common ingredients in toothpaste and mouthwash, due to their effect in the prevention of dental caries.However, use too much of fluoride products for oral hygiene is one of factors that may be a potentially toxic for children. The aim of this study was to determine a content of fluoride in five different types of toothpaste and five different types of mouthwashes commercially available on the Bosnian and Herzegovinian markets and based on a certain content of fluoride, to show the exposure of children to fluorides from the toothpaste and mouthwash. The fluoridecontent was determined by a simple, fast and economical potentiometric method using fluoride ion-selective electrode..........

 

Keywords: Toothpaste, Mouthwash, Fluoride, Fluoride ion-selective electrode, Potentiometry.

[1]. Bralić M, Buljac M, Prkić A, Buzuk M, &Brinić S. Determination Fluoride in Products for Oral Hygiene Using Flow-Injection (FIA) and Continuous Analysis (CA) with Home-Made FISE. Int. J. Electrochem. Sci, 2015: 10, 2253-2264.
[2]. Sunitha V, & Reddy BM. Determination of fluoride concentration in ground water by ion selective electrode. Int. J. Curr. Res. Aca Rev, 2014: 2, 159-166.
[3]. Seraj B, Shahrabi M, Shadfar M, Ahmadi R, Fallahzadeh M, Eslamlu HF, &Kharazifard MJ. Effect of high water fluoride concentration on the intellectual development of children in makoo/iran. Journal of dentistry (Tehran, Iran), 2012: 9(3), 221.
[4]. Spencer AJ, Do L., Mueller U, Baines J, Foley M, & Peres MA. Understanding optimum fluoride intake from population-level evidence. Advances in dental research, 2018: 29(2), 144-156.
[5]. Gleisner H, Einax JW, Morés S, Welz B, &Carasek E. A fast and accurate method for the determination of total and soluble fluorine in toothpaste using high-resolution graphite furnace molecular absorption spectrometry and its comparison with established techniques. Journal of pharmaceutical and biomedical analysis, 2011: 54(5), 1040-1046.

 

Paper Type

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Research Paper

Title

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Synthesis & characterization studies of some derivatives of 1, 4-Naphthoquinone substituted C1-NOH, C2-NH2, (N-acetyl) acetamido and C3-Cl

Country

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India

Authors

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Shubhangi V. Kulkarni || Raghunath G. Sarawadekar || Avinash B. Pawar

Page No.

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51-57

Paper Index
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XXXX

The invention relates to a material for destructing micro algae with specific substituents. The compounds contain 1, 4 - Naphthoquinone as a basic one and substitution is carried out at C1, C2, and C3 (C1-NOH, C2-NH2 or (N-Acetyl) - acetamido and C3-Cl). Amino Naphthoquinone can be embedded on cotton fabrics for good durability. Synthesis of 2-Amino-3-Chloro-1,4- Naphthoquinone (L1), 2-(N-acetyl) – acetamido-3-Chloro-1,4 – Naphthoquinone(L2), 2-Amino-3-Chloro-1,4-Naphthoquinone-1,Oxime(L3)and2-(N-acetyl)–acetamido-3-Chloro-1,4Naphthoquinone-1,Oxime (L4) were carried out. X-ray diffraction studies show that all these ligands are crystalline in nature and belongs to triclinic group. Crystalline parameters and h, k, l values are calculated by using McMallie computer code. The crystalline size is determined by Scherrer formula and found to be L1-58.045 nm, L2-48.314 nm, L3- 64.97 nm and L4- 49.54 nm. Infrared spectra shows characteristic frequencies for C-H, N-H, C=O, C=C and C-N. UV-VIS spectra shows electronic transition for π → π *, n→ π*. The results are discussed in this paper.

 

Keywords: 2-Amino-3-Chloro-1, 4- Naphthoquinone, XRD, IR

[1]. Liu, Jun O,: Oaleye, OmonikeArike: Bhat, Shridhar, "Preparation of Naphthoquinone and Naphthothiazole compounds as therapeutic inhibitors of methionine amino peptidases", PCT Int. Appl. WO 2011017519 A2 20110210(2011).
[2]. Scherzer, Roni: Gazit, Ehud: Segal, Daniel,"Naphthoquinone derivatives useful for prevention of amyloid deposits and treatment of diseases involving amyloid genesis", PCT Int. Appl. WO 2010026592 A1 20100311 (2010),.
[3]. Lee, KuoHsiung: Kuo, Sheng-Chu: ibuka, Toshiro, "Preparation of naphtha(2,3-d) imidazole-4,9-diones and analogs as antitumor agents", PCT Int. Appl. WO 9730022 A1 19970821(1997),.
[4]. Cho, Hun:, "Composition containing Naphthoquinone for controlling microalgae",Repub, Korian Kongkae Taeho Kongbo KR 2014105423 A 20140901(2014),.
[5]. Russell, Angela Jane:Sim, Edith: Daviess, Steven Graham: Westowood, Isaac Mark: Kawamura, Akane: Crawfprd Matthew Howard James: Laurieri, Nicola, "Preparation of Naphthoquinone derivatives for us as hNAT1 inhibitors useful in treatment of breast cancer", PCT Int. Appl. WO 2011055142 A2 20110512 (2011),.

 

Paper Type

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Research Paper

Title

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A Descriptive Study On Hygiene And Culinary Hygiene Based On Dietary Pattern And Life Style

Country

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India

Authors

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E.Vikrant Reddy || B. Hari Krishna || G.Jaswanth || G. Sriramya Jyothi || R.Monica Pravallika || Rajini Sudireddy || Dr.M.Parasada Rao

Page No.

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58-60

Paper Index
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XXXX

Objective: To find out personal hygiene and culinary hygiene among the patients with communicable diseases1 with age group 12-50 years. Method: Prospective Observational Study was conducted at Nikhil hospital, Narsaraopet. Two hundred and twenty-six patients (N=226) participated in the study. The self-assessed questionnaire was used to identify patients with personal hygiene and culinary hygiene. Results: It is interpreted 44.20% Male and 33.70% female were observed to be with poor hygiene. In the study population, 50 patients were hygienic and 176 patients were having poor hygiene and culinary hygiene. Conclusion: This study clearly depicts poor hygiene and culinary in patients. There is an immediate need for patient-centered3 clinics and clinical pharmacist4 to be employed to counsel and educate the patients.

 

Keywords: (1)communicable disease (2) culinary hygiene(3)patient-centered(4)clinical pharmacist.

[1]. Martín Moreno V1, Molina Cabrerizo MR, Fernández Rodríguez J, Moreno Fernández AM, Lucas Valbuena JCDietary and personal hygiene habits of adolescents in a rural population,PubMed1996 May-Jun;70(3):331-43 [2]. Arija V, Salas Salvadó J, Fernández-Ballart J, Cucó G, Martí-Henneberg. Consumo. hábitosalimentarios y estadonutricional de la población de Reus (VIII). Evolución de la ingestión de energía y nutrientes entre 1983 y 1993. Med Clin (Barc) 1996; 106: 45-50. [3]. Dietz WH, Gortmaker SL. Do we fatten our children at the television set?. Obesity and television viewing in children and adolescents. Pediatrics 1985; 75: 807-812.
[4]. MMWR. Results from the national adolescent student health survey. JAMA 1989, 261: 3025- 2031.
[5]. LópezNomdedeu C. Los alimentos. En: Alimentación y Nutrición, no 3. Ministerio de Sanidad y Consumo, Madrid 1989

 

Paper Type

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Research Paper

Title

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Evaluation of Pulmonary Function Parameters in Street Vendors of Telangana Region Using Portable Spirometer

Country

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India

Authors

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M.Nethaji || Md.Younus || B.Sandeep || D.Sudheer kumar || P.Kishore

Page No.

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61-68

Paper Index
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XXXX

The association between exposure to pollution and pulmonary function was studied in street vendors using a portable handheld spirometer. The aim of this study was to evaluate the extent of impairment in lung function in street vendors compared to the general population (control group). It is a prospective observational study conducted in the Warangal region for a period of 7 months. This study was conducted by collecting and assessing the various pulmonary parameters using portable spirometry on 300 street vendors (test group) and general population (control group). We observed that Street vendors had a significant decline in pulmonary function parameters. Of total, 60.7 % had abnormal Peak expiratory flow (PEF), 43 % had abnormal Forced Expiratory Volume in 1 second (FEV1), 35.6 % had abnormal Forced Vital Capacity (FVC), whereas there were negligible changes in the pulmonary function parameters of the general population...........

 

Keywords: Forced Vital Capacity (FVC), Peak expiratory flow (PEF), Spirometry, Street vendors.

[1]. Adeladza Kofi Amegah, JouniJ.K.Jaakkola. Work as a street vendor, associated traffic-related air pollution exposures and risk of adverse pregnancy outcomes in Accra, Ghana,International Journal of Hygiene and Environmental Health,(217), 2014,354–362.
[2]. Wahlin, P.Palmgren, F.Dingenen, R.V.Experimental studies of ultrafine particles in streets and the relationship to traffic, Atmospheric environment, 35 (1), 2001, S63–S69.
[3]. Watson KE. Air pollution and heart disease, Rev Cardiovasc Med, (7), 2006,44.
[4]. Scarborough P, Allender S, Rayner M, et al. Contribution of climate and air pollution to variation in coronary heart disease mortality rates in England. PLoS one,7.2012,e32787.
[5]. Rückerl R, Ibald-Mulli A, Koenig W, et al. Air pollution and markers of inflammation and coagulation in patients with coronary heart disease. Am J RespirCrit Care Med173,2006, 432-441.

 

Paper Type

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Research Paper

Title

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Morphological On the FT-IR Spectra, XRD and EDX Studies in Adsorption of Methylene Blue Dye Present in Aqueous Solution onto Acid Activated Carbon Prepared From Mimusops Elengi Leaves

Country

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India

Authors

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A.Elavarasan

Page No.

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69-74

Paper Index
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XXXX

Adsorption studies were carried out by observing the effects of various experimental parameters removal of Methylene blue from aqueous solution. Morphology of adsorbent due to adsorption have been analyzed PH, FT-IR spectra, EDX and XRD analysis.The data were fitted into the Langmuir and Freundlich adsorption isotherm equations. Thermodynamics parameters like change in free energy, enthalpy and entropy were calculated.

 

Keywords: PH, FT-IR spectra, EDX and XRD analysis.

[1]. Gleeson, Tom, Wada, Yoshihide, Bierkens, Marc F. P, van Beek, and Ludovicus P. H , Nature, 488 (7410), (9 august 2012), 197–200.
[2]. http://www.wikiwand.com/en/Water_pollution.
[3]. Contaminants may include organic and inorganic, www.coursehero.com/file/p2jjv35/ Contaminants-may-include-organic-and inorganic-substances-Organic-water/. [4]. Vijayaraghavan K and Yun Y S, Bacterial biosorbents and biosorption, j.biotechadv, (26) 3, (2008may-jun).
[5]. Tarun Kumar Naiya1, BiswajitSingha2 and Sudip Kumar Das2, FTIR Study for the Cr(VI) Removal from Aqueous Solution Using Rice Waste, International Conference on Chemistry and Chemical Process IPCBEE vol.10 (2011).

 

Paper Type

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Research Paper

Title

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Relationship among Pregnancy Associated Plasma Protein-A(PAPP-A) Gene Expression, Serum PAPP-A and Insulin levels in Patients with Preeclampsia in Egyptian Women

Country

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Egypt

Authors

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Amal K. Seleem || A. A. Abdel Aziz || Hosam Abdelfatah || M. S. A.El-Gharib || Faeza El-Dahtory || Eatimad A. Basha

Page No.

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75-83

Paper Index
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XXXX

To assess PAPP-A gene expression, serumPAPP-A and insulin levels in maternal blood of preeclamptics and to compare them with normotensive pregnant women.Control 60 women withPreeclampsia and 30Nonpreeclampsianormotensive women as control. Three groups were chosen; mild preeclampsia group 30 women, severe preeclampsia group 30and control group 30 women. Maternal blood samples for PAPP-AandInsulin were collected from the patients at second trimester and compared. Term placentas were collected from Egyptian women delivering at University Hospitalfrom the gynecological and ObstetricsDepartment, Mansoura University, two hours of delivery. Expression of the PAPPA gene was assayed by quantitative real time PCR. Serum PAPPA levelswere lowered in maternal blood of preeclamptic as compared to normotensive mothers (P < 0.001)............

 

Keywords: Insulin; PAPPA, Gene Expression, Preeclampsia.

[1] J. Wang, Q. Qiu, M. Haider, M. Bell, A. Gruslin, and J.K. Christians, Expression of pregnancy-associated plasma protein A2 during pregnancy in human and mouse.J Endocrinol,202(3),2009,337-345.
[2] L.S. Laursen, M.T. Overgaard, R. Soe, H.B. Boldt, L. Sottrup-Jensen, L.C. Giudice, C.A. Conover, and C. Oxvig, Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A.FEBS Lett,504(1-2),2001,36-40.
[3] S. Shiefa, M. Amargandhi, J. Bhupendra, S. Moulali, and T. Kristine, First Trimester Maternal Serum Screening Using Biochemical Markers PAPP-A and Free β-hCG for Down Syndrome, Patau Syndrome and Edward Syndrome.Indian Journal of Clinical Biochemistry,28(1),2013,3-12.
[4] N. Furukawa and E. Araki, [Type 2 diabetes and impaired glucose tolerance].Nihon Rinsho,71(2),2013,270-274.
[5] Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy.Am J Obstet Gynecol,183(1),2000,S1-s22.