Volume 8 ~ Issue 8,~Version 2, ~ August - 2018


Paper Type

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Research Paper

Title

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Assessment of Genetic Variability and Selection Parameter For Yield Contributing Traits In Maize (Zea mays L.)

Country

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India

Authors

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Vishwanath || Lokendra Singh || P. C. Yadav || Sanjeev Kumar || H. C. Singh || R. K. Yadav || Yogesh Pandey || Sarvendra Gupta

Page No.

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01-03

Paper Index
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XXXX

In the present study, ten parents of maize were crossed in half diallel fashion to evaluate, 45 F1,s and 45 F2,s and ten parents for assessment of genetic varability and selection parameters in grain yield and related attributes during Kharif 2015 in Complete Randomized Block Design with three replication at C. S. Azad University of agriculture and Technology, Kanpur. Analysis of variance was recorded significant differences for all the traits in parents revealing the genetic diversity among the maize genotype. The moderate PCV as well as GCV were observed for cob diameter (11.43 and 12.89 per cent) and cob length (12.61 and 13.50 per cent) in F1 generation. The moderate PCV as well as GCV were observed for cob diameter (13.33 and 12.10 per cent) and cob length (12.55 and 13.65 per cent) in F2 generation..........

 

Keywords: Genetic variability, GCV, PCV, Heritability and Genetic advance in maize.

[1]. Kanagarasu, S., Nallathambi, G., Kannan, S. and Ganesan, K. N. (2013). Genetic variability and association analysis for yield and its components in single cross hybrids of maize (Zea mays L.). Electronic Journal of Plant Breeding; 4(4):1319-1324.
[2]. Maruthi, R. T. and Rani, K. J. (2015) Genetic variability, heritability and genetic advance estimates in maize (Zea mays L.) inbred lines. Journal of Applied and Natural Science; 7(1):149-154.
[3]. Nayak, V. H. Rajesh Singh Potla, K. R.(2013) Genetic variability analysis of yield and yield related traits in inbred lines of maize (Zea mays L.) Environment and Ecology; 31(4):1669-1671.
[4]. Satyanarayana, E., Shanthi, P., Rekha, P. M. and Kumar, R. S. (2003). Studies on the identification of suitable parents from high-oil maize (Zea mays L.) germplasm for making potential single cross hybrids Research on Crops; 4(3):348-354.
[5]. Sharma,R., Maloo, S. R. and Joshi, A. (2014). Genetic variability analysis in diverse maize genotypes (Zea mays L.) Electronic Journal of Plant Breeding; 5(3):545-551.

 

Paper Type

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Research Paper

Title

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Synthesis and antimycobacterialactivity againstMycobacterium tuberculosis (MTB) H37Rv of some novel Indolederivatives

Country

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India

Authors

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Dr. B.P. Yadav || Dr. Ajit Joshi || Iftakhar Ahmad

Page No.

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04-08

Paper Index
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XXXX

Tuberculosis treatment remnants a contest that necessitates new antitubercular agents due to the development of multidrug-resistant Mycobacterium strains. This paper defines the synthesis, characterization and the antitubercular activity of some new 2-ethyl 1-alkyl 5-chloro-3-(pyridin-3-yl)-1H-indole-1,2-dicarboxylatederivatives, alkyl 2-(alkylcarbamoyl)-5-chloro-3-(pyridin-3-yl)-1H-indole-1-carboxylate and 2-ethyl 1-alkyl 5-chloro-3-cyclopropyl-1H-indole-1,2-dicarboxylate, alkyl 2-(methylcarbamoyl)-5-chloro-3-cyclopropyl-1H-indole-1-carboxylatederivatives, which were synthesized by the C-C coupling (Suzuki coupling) reaction. This reaction involve coupling of ethyl 3-bromo-5-chloro-1H-indole-2-carboxylate............

 

Keywords: Indole derivative,antitubercular activity, minimum inhibitory concentration, minimum fungicidal concentration.

[1]. Shinnick, T. M.; King, C. H.; Quinn, F. D. Am. J. Med. Sci.,1995, 309, 92.
[2]. Snider, D. E., Jr.; La Montagne, J. R. J. Infect. Dis.,1994, 169, 1189.
[3]. Pablos-Mendez, A.; Raviglione, M. C.; Laszlo, A.; Binkin, N.; Rieder, H. L.; Bustreo, F.; Cohn, D. L.; Lambregtsvan Weezenbeek, C. S.; Kim, S. J.; Cahulet, P.; Nunn, P. N. Eng. J. Med.,1998, 338, 1641.
[4]. Houston, S.; Fanning, A. Drugs,1994, 48, 689.
[5]. Cocco, M. T.; Congiu, C.; Onnis, V.; Pellerano, M. L.; De Logu, A.,Bioorg. Med. Chem.,2002, 10, 501.

 

Paper Type

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Research Paper

Title

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What's standing in the way of Clinical Pharmacy in India: Understanding History, Development and Issues plaguing it

Country

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India

Authors

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Ankit Gaur || Irfanul Haque || Madan Ram || Sai Charan || Ashish Akshay Bedi || Deepanshu Kumar Chitra

Page No.

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09-16

Paper Index
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XXXX

India's great cultural diversity is reflected in its healthcare system and it is also a country with significant drug-use problems. The major contributor in combating these problems can be the clinical pharmacists. In this article we tried to shed some light on questions such as how India accomplished the task of introducing the clinical pharmacy, how this is similar to the paradigm shift that took place in western countries, what are the current issues plaguing it, what lessons can be learned from the past experiences which can be implemented in India to pave the way for rise of clinical pharmacists as an effective member of healthcare team in Indian healthcare system.

 

Keywords: Clinical Pharmacist, Clinical Pharmacy, Pharm.D, Pharmacy Practice, Doctor of Pharmacy.

[1]. Nyfort-hansen K, May F. Clinical Pharmacy A New Beginning in India. Aust J Hosp Pharm. 1998;28(5):343–7.
[2]. Porter G, Grills N. Medication misuse in India: A major public health issue in India. J Public Heal (United Kingdom). 2016;38(2):150–7.
[3]. Central Bureau of Health Intelligence. National Health Profile of India - 2018. 2018;(13):310.
[4]. World Health Organization. Not Enough Here ... Too Many There ...Health Workforce in India. 2007.
[5]. Pharmacy Council of India. Annual Report on the Activities of the Council during 2015-2016. Annual Report. 2013. Available from: http://www.pci.nic.in/pdf/AnnualReport(2015-2016).pdf

 

Paper Type

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Research Paper

Title

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A Study On Laminectomy, Discectomy And Conservative Management For Prolapsed Intervertebral Disc And Assessment Of Recurrent Disc Herniation

Country

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India

Authors

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Sadiya Sabreen || D.Ankith Reddy || T.Divya || P.Kishore || N.Laxmi Prasad || D.Sudheer kumar || P.Durga

Page No.

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17-23

Paper Index
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XXXX

Disc herniation is one of the most frequent diseases in lumbar (L), cervical (C) region and the affected disc site is L4-S1 and C3-C4. Higher the degree of disc herniation, higher the likelihood of LBP. The aim of the study is to find out the functional outcomes of the laminectomy, discectomy in pre and post-operative, conservatively treated patients and assessment of recurrent disc herniation, to elucidate the risk factors of the PIVD. It is a prospective study conducted in 408 patients, among them 58 patients underwent surgical treatment and 350 patients were treated conservatively. 92 % of the patient population has shown significant p (0.0001) value with good to excellent outcome in surgical management with 6 months of follow-up. Whereas in conservatively treated.........

 

Keywords: PIVD (Prolapsed intervertebral disc), LBP (Low back pain), Disc herniation, Laminectomy, Discectomy.

[1]. Carroll LJ, Cassidy JD, Côté P (2000) The Saskatchewan Health and Back Pain Survey: the prevalence and factors associated with depressive symptomatology in Saskatchewan adults. Can J Public Health 91: 459-464.
[2]. Daoyou Ma, Yunbiao liang, Daoming Wang, Zejiang liu, Wei Zhang, Tantan Ma, liang Zhang, Xingjun lu, Zhiyou Cai. "Trend of the incidence of lumbar disc herniation: decreasing with aging in the elderly, Clinical Interventions in Aging". 2013:8 1047–1050.
[3]. Jo Jordan, kika konstantinou, John O‟ Dowd. "Herniated lumbar disc." Clinical Evidence BMJ 2009.
[4]. Jani T akatalo, MSc , Jaro Karppinen, MD, PhD, Jaakko Niinimäk ,MD, PhD, Simo T aimela, MD, PhD, Pertti M utanen , MSc , Roberto Blanco Sequeiros, MD, PhD, Simo Näyhä, MD, PhD, Marjo-Riitta Järvelin, MD, PhD. "Association of Modic Changes, Schmorl‟s Nodes, Spondylolytic Defects, High-Intensity Zone Lesions, Disc Herniations, and Radial Tears With Low Back Symptom Severity Among Young Finnish Adults." SPINE 37; (14), pp 1231–1239 ©2012, Lippincott Williams & Wilkins.
[5]. Laser spine institute, [https://www.laserspineinstitute.com/back_problems/degenerative_spine]

 

Paper Type

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Research Paper

Title

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Antioxidant activity of polysaccharide from Sargassum sp

Country

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India

Authors

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Revathi Chitra S || Syed Ali M || Anuradha V || Shantha M || Yogananth

Page No.

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24-31

Paper Index
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XXXX

Brown seaweeds are widely used in the medical field to treat tumor cells. In this present study brown seaweed Sargassum species was used to isolate polysaccharide and quantitative estimation of carbohydrate was done and the free radical scavenging activity of the isolated polysaccharide was determined using DPPH radical scavenging assay, Hydrogen peroxide scavenging activity Nitric oxide scavenging activity , Ferric reducing antioxidant Power (FRAP) Deoxyribose Radical Scavenging Activity, ABTS [2, 2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)] Radical cation Scavenging Assay, Superoxide radical scavenging activity, Estimation of lipid peroxidation using egg yolks, β carotene linoleic acid assay and SOD was performed. The obtained results gave a significant IC50 Value which indicates that the isolated polysaccharide from the Sargassum sp was able to inhibit the free radicals and can be used to treat tumour cells.

 

Keywords: Anticancer activity, Fucoidan, Fucose, polysaccharide, Sargassum sp.

[1]. Asker, M.S., Mohammed, S.M., Ali, F.M., El-Sayed, O.H., 2007. Chemical structure and antiviral activity of water-soluble sulfated polysaccharides from Sargassum latifolium. J. Appl. Sci. Res. 3, 1178–1185.[1].

[2]. Josephine, A, Veena, C.K., Amudha, G., Preetha, S.P., Sundarapandian, R.,Varalakshmi, P, 2007. Sulphated polysaccharides: new insight in the prevention of cyclosporine A-induced glomerular injury. Basic Clin. Pharmacol. Toxicol. 101, 9–15.[2]

[3]. Patankar MS, Oehninger S, Barnett T, Williams RL, Clark GF (1993) A Revised Structure for Fucoidan May Explain Some of Its Biological Activities. J Biol Chem 268: 21770-21776.[3]

[4]. Eluvakkal T, Sivakumar SR, Arunkumar K (2010) Fucoidan in Some Indian Brown Seaweeds Found along the Coast Gulf of Mannar. International Journal of Botany 6: 176-181[4]
[5]. Balakumar K, Ramanathan S Kumaresan and Suresh R (2010) DNA damage by sodium arsenite in experimental rats: ameliorative effects of antioxidant vitamins C and E[5].

 

Paper Type

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Research Paper

Title

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Traditional uses of Iraqi medicinal plants

Country

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Iraq

Authors

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Prof Dr Ali Esmail Al-Snafi

Page No.

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32-95

Paper Index
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XXXX

This study illustrates the importance of Iraqi medicinal plants in the treatment and management of human diseases and ailments as known by traditional medicine.

 

Keywords: ------------

[1]. Pengelly A. The constituents of medicinal plants: An introduction to the chemistry and therapeutics of herbal medicine. CABI publishing, Wallingford, 2004.
[2]. Orhan IE. Biotechnological production of plant secondary metabolites. Bentham ebook. 2012:107.
[3]. Al-Snafi AE. Encyclopedia of the constituents and pharmacological effects of Iraqi medicinal plants. Rigi Publication, India, 2015
[4]. Khan MA. Chemical constituents of Centaurea iberica and Achillea santolina, and synthesis of myoglobin and insulin. PhD thesis, University of Karachi, 1998.
[5]. Al-Hindawi MK, Al-Deen IH and Nabi MH. Anti-inflammatory activity of some Iraqi plants using intact rats. J Ethnopharmacol 1989; 26:163-168.